Results 121 to 130 of about 6,263,550 (261)

Peptide-based materials: from nanostructures to applications

This special issue originates from the Symposium C entitled ‘Peptide-based materials: from nanostructures to applications’, held during the 2010 Spring Conference of the European Materials Research Society (Strasbourg, June 5–11, 2010).Peer ...
Venanzi, M., Bianco, Alberto, Alemán Llansó, Carlos   +2 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Engineering and Exploiting Immobilized Peptide Organocatalysts for Modern Synthesis

Molecules
Short- and medium-sized peptides have long been used as effective and versatile organocatalysts. In the early 80s, Inoue used diketopiperazines in the Strecker reaction, while Juliá and Colonna reported the epoxidation of chalcone catalyzed by poly-L-Ala.
Marco Francescato, Hang Liao, Luca Gentilucci   +2 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Peptide-Directed Supramolecular Self-Assembly of N-Substituted Perylene Imides

, 2015
Synthetic peptides offer enormous potential to encode the assembly of molecular electronic components, provided that the complex range of interactions is distilled into simple design rules.
Eakins, Galen (11705639)
core   +1 more source

On the origin of spontaneous electrical oscillations in a minimal peptide assembly

Materials & Design
The design of functional materials involves understanding how complex functionalities can emerge from simple material building blocks. In this context, peptide-based systems represent a versatile materials platform due to their chemical diversity ...
Salvatore Del Basso, Pietro Squeri, Rishit Mohan Ahuja, Rishav Karki, Giuseppe De Giorgio, Vardan Galstyan, Raffaele Martucci Zecca, Enrico Dalcanale, Xiongchuan Huang, Davide Vurro, Saksham Sharma, Pasquale D’Angelo, Andrew Adamatzky, Giuseppe Tarabella   +13 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Alloreactive cytotoxic T lymphocytes generated in the presence of viral- derived peptides show exquisite peptide and MHC specificity [PDF]

, 1993
The nature of alloreactivity to MHC molecules has been enigmatic, primarily because of the observation that allogeneic responses are considerably stronger than syngeneic responses. To better determine the specificity potential of allogeneic responses, we
Connolly, J. M., Koszinowski, Ulrich H., Alexander-Miller, M. A., Burke, K., Hansen, T. H.   +4 more
core  

Nanostructured materials based on mesoporous silica and mesoporous silica/apatite as osteogenic growth peptide carriers

, 2013
The aim of this work was the preparation of inorganic mesoporous materials from silica, calcium phosphate and a nonionic surfactant and to evaluate the incorporation and release of different concentrations of osteogenic growth peptide (OGP) for ...
Martines, M. A U, Marchetto, Reinaldo [UNESP], Mendes, L. S., Marchetto, Reinaldo, Mendes, L. S. [UNESP], Saska, S. [UNESP], Saska, S.   +6 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source