Results 201 to 210 of about 344,433 (343)

Development of a Novel Peptide Nucleic Acid Probe for the Detection of Legionella spp. in Water Samples. [PDF]

open access: yesMicroorganisms, 2022
Nácher-Vázquez M   +8 more
europepmc   +1 more source

Detection of endothelin receptor subtypes mRNA in paraffin sections by in situ hybridization using peptide nucleic acid probes in human cirrhotic liver

open access: bronze, 2000
Hiroaki Yokomori   +5 more
openalex   +1 more source

One-Step Detection of c-kit Point Mutations Using Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping and Hybridization Probes [PDF]

open access: bronze, 2003
Karl Sotlar   +8 more
openalex   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

open access: yesAdvanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu   +16 more
wiley   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen   +14 more
wiley   +1 more source

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