Peptide nucleic acid-assisted generation of targeted double-stranded DNA breaks with T7 endonuclease I. [PDF]
Aman R+8 more
europepmc +1 more source
Exploring a peptide nucleic acid-based antisense approach for CD5 targeting in chronic lymphocytic leukemia. [PDF]
Cesaro E+13 more
europepmc +1 more source
359. Enhanced Gene Delivery by a Novel Tumor-Specific Vector Containing Peptide and Nucleic Acid Based Nuclear Translocation Signals [PDF]
Stanley Saamoah-Moffatt+2 more
openalex +1 more source
A self‐assembling, aggregation‐enhanced tetrahedral DNA nanostructure (tFNA), termed TACs, enables localized accumulation and sustained release of ceftriaxone while co‐delivering antisense oligonucleotides that silence mecA, reduce PBP2a expression, and restore β‐lactam susceptibility in MRSA.
Yicheng Zhao+10 more
wiley +1 more source
Novel diagnostic biomarkers for pancreatic cancer: assessing methylation status with epigenetic-specific peptide nucleic acid and KRAS mutation in cell-free DNA. [PDF]
Kim H+11 more
europepmc +1 more source
Magnetic Nanoparticle-Based Electrochemical Sensing Platform Using Ferrocene-Labelled Peptide Nucleic Acid for the Early Diagnosis of Colorectal Cancer. [PDF]
Hanoglu SB+15 more
europepmc +1 more source
Introduction of Peptide Functions into DNA by Nucleic Acid Peptides, NAPs [PDF]
Junji Kawakami+4 more
openalex +1 more source
This study introduces an immunomodulatory DNA tetrahedral framework nucleic acid‐based nanovaccine tFNA‐CpG. The functionalized nanovaccine shows stable and well‐defined morphological characteristics and can be efficiently taken up by APCs. When combined with the immune checkpoint inhibitor anti‐PD‐1, it notably ameliorated the immunosuppressive ...
Xueting Yang+12 more
wiley +1 more source
The peptide nucleic acids (PNAs) as probes for chromosomal analysis of human oocytes and preimplantation embryos [PDF]
Franck Pellestor+5 more
openalex +1 more source