Results 201 to 210 of about 686,761 (347)

De Novo Potent Peptide Nucleic Acid Antisense Oligomer Inhibitors Targeting SARS-CoV-2 RNA-Dependent RNA Polymerase via Structure-Guided Drug Design. [PDF]

Int J Mol Sci, 2023
Shehzadi K, Yu M, Liang J.
europepmc   +1 more source

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease [PDF]

, 2001
Aleksandra Muratovska, Robert N. Lightowlers, Robert W. Taylor, Douglass M. Turnbull, Robin A.J. Smith, Matthew C. J. Wilce, Stephen W. Martin, Michael P. Murphy   +7 more
openalex   +1 more source

Programmable Stapling Peptide Based on Sulfonium as Universal Vaccine Adjuvants for Multiple Types of Vaccines

Advanced Science, Volume 12, Issue 11, March 20, 2025.
A stapling peptide with two sulfonium centers is developed to be used as an excellent vaccine adjuvant candidate for the Hepatitis B vaccine, influenza vaccine, and herpes zoster vaccine. Just by changing the amino acids and ring types, it is easy to program peptide adjuvants to adapt to multiple vaccine subtypes and synergistically induce humoral and ...
Yaping Zhang, Chenshan Lian, Wenlong Lai, Leying Jiang, Yun Xing, Huiting Liang, Jin Li, Xinming Zhang, Jianhui Gan, Zigang Li, Feng Yin   +10 more
wiley   +1 more source

Rapid extraction-free detection of the R132H isocitrate dehydrogenase mutation in glioma using colorimetric peptide nucleic acid-loop mediated isothermal amplification (CPNA-LAMP). [PDF]

PLoS One, 2023
Choate KA, Raack EJ, Line VF, Jennings MJ, Belton RJ, Winn RJ, Mann PB.   +6 more
europepmc   +1 more source

In Situ Hybridization of Prochlorococcus and Synechococcus (Marine Cyanobacteria) spp. with rRNA-Targeted Peptide Nucleic Acid Probes

, 2000
Alexandra Z. Worden, Sallie W. Chisholm, Brian J. Binder   +2 more
openalex   +1 more source

Detection and identification of lactic acid bacteria in milk and industrial starter culture with fluorescently labeled rRNA-targeted peptide nucleic acid probes [PDF]

, 2001
Oriane Matte-Tailliez, Pascal Quénée, Recep Çıbık, Jacques van Opstal, Fabrice Dessevre, Olivier Firmesse, Patrick Tailliez   +6 more
openalex   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Topical Application of Peptide Nucleic Acid Antisense Oligonucleotide for MMP-1 and Its Potential Anti-Aging Properties. [PDF]

J Clin Med, 2023
Lee YI, Lee SG, Jung I, Suk J, Baeg C, Han SY, Seo JY, Jung D, Jeon Y, Lee JH.   +9 more
europepmc   +1 more source

Randomized, Placebo-Controlled Trial of Product R, a Peptide-Nucleic Acid Immunomodulator, in the Treatment of Adults Infected with HIV [PDF]

, 2002
Levett Paul N., Hirschman Shalom Z., Roach Timothy C, Broome Hedy, Alexander Richard J, Henry S. Fraser   +5 more
openalex   +1 more source

Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies

Advanced Science, Volume 12, Issue 14, April 10, 2025.
This review article delves into the cutting‐edge advancements in gene editing technology, with a particular focus on prime editor proteins and their engineered variants. The authors provide a thorough examination of recent developments that have addressed key challenges in the field, including improved precision, enhanced editing efficiency, and ...
Abhijith Koodamvetty, Saravanabhavan Thangavel   +1 more
wiley   +1 more source