Results 251 to 260 of about 344,433 (343)

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity [PDF]

, 2004
Carlo Mischiati, Alessia Sereni, Alessia Finotti, Laura Breda, Rita Cortesi, Claudio Nastruzzi, Alessandra Romanelli, Michele Saviano, Nicoletta Bianchi, Carlo Pedone, Monica Borgatti, Roberto Gambari   +11 more
openalex   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

Advanced Science, EarlyView.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, Qin Wang, Jinhan Wang, Chang Xu, Liqing Du, Saijun Fan, Feng Wang, Qiang Liu, Yang Liu   +17 more
wiley   +1 more source

The Design of a Participatory Peptide Nucleic Acid Duplex Crosslinker to Enhance the Stiffness of Self-Assembled Peptide Gels. [PDF]

Angew Chem Int Ed Engl
Sakar S, Anderson CF, Schneider JP.
europepmc   +1 more source

Editor's note on 'down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates'. [PDF]

Nucleic Acids Res, 2023
europepmc   +1 more source

Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids [PDF]

, 2005
Karen T. Duffy, Mary Frances McAleer, William R. Davidson, Laszlo Kari, Csaba Kari, Chunxiao Liu, Steven Farber, Keith C. Cheng, Jason R. Mest, Eric Wickstrom, Adam P. Dicker, Ulrich Rodeck   +11 more
openalex   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

Rapid Identification of Staphylococcus aureus in Blood Cultures by a Combination of Fluorescence In Situ Hybridization Using Peptide Nucleic Acid Probes and Flow Cytometry [PDF]

, 2005
Hanna Hartmann, Henrik Stender, Andrea Schäfer, Ingo B. Autenrieth, Volkhard A. J. Kempf   +4 more
openalex   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

Direct Identification of Major Blood Culture Pathogens, Including Pseudomonas aeruginosa and Escherichia coli , by a Panel of Fluorescence In Situ Hybridization Assays Using Peptide Nucleic Acid Probes [PDF]

, 2005
Mette Søgaard, Henrik Stender, Henrik Carl Schønheyder   +2 more
openalex   +1 more source

A Molecular Recruitment Colocalization Platform for Visualizing Multi‐Protein Interactions and Engineering Biomolecular Condensates in Living Cells

Advanced Science, EarlyView.
MRC is a live‐cell method enabling visualization of protein–protein interactions and biomolecular condensates. It supports multi‐protein colocalization, binding analysis, and programmable condensate manipulation, providing a versatile platform for studying dynamic cellular organization.
Lei Peng, Yu Hou, Yan Zhao, Jing‐Ya Tang, Liu Song, Bo Peng, Min Li, Dian‐Bing Wang, Xian‐En Zhang   +8 more
wiley   +1 more source