Peptide nucleic acid (PNA) binding-mediated gene regulation [PDF]
, 2004 Gan Wang, Xiaoxin Xu
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Advanced Science, EarlyView.This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng +8 more
wiley +1 more source
Cyclopentane peptide nucleic acid: Gold nanoparticle conjugates for the detection of nucleic acids in a microfluidic format. [PDF]
Biopolymers, 2022 Amarasekara H +6 more
europepmc +1 more source
Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles [PDF]
, 2004 D.M. Murphy +3 more
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Advanced Science, Volume 12, Issue 16, April 24, 2025.This study explores the role of gemcitabine (GEM)‐resistant pancreatic cancer‐derived extracellular vesicles (EVs) in activating pancreatic stellate cells (PSCs) and promoting extracellular matrix production. GEM‐resistant cells release higher levels of asparagine (Asn), which triggers PSC activation. Long noncoding RNA sequencing identified linc‐ZNF25‐
Miao Yu +6 more
wiley +1 more source
359. Enhanced Gene Delivery by a Novel Tumor-Specific Vector Containing Peptide and Nucleic Acid Based Nuclear Translocation Signals [PDF]
, 2004 Stanley Saamoah-Moffatt +2 more
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Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
Advanced Science, EarlyView.The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan +16 more
wiley +1 more source
Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications. [PDF]
RSC Chem Biol, 2022 Suparpprom C, Vilaivan T.
europepmc +1 more source
Peptide nucleic acids on microarrays and other biosensors [PDF]
, 2004 Ole Brandt, Jörg D. Hoheisel
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Engineering the Immune Response to Biomaterials
Advanced Science, EarlyView.This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam +12 more
wiley +1 more source