Advanced Healthcare Materials, EarlyView.PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall +14 more
wiley +1 more source
Chiral Peptide Nucleic Acids with a Substituent in the N-(2-Aminoethy)glycine Backbone
Molecules, 2012 A peptide nucleic acid (PNA) is a synthetic nucleic acid mimic in which the sugar-phosphate backbone is replaced by a peptide backbone. PNAs hybridize to complementary DNA and RNA with higher affinity and superior sequence selectivity compared to DNA ...
Atsushi Kittaka, Toru Sugiyama
doaj +1 more source
An Efficient Synthetic Strategy for the Preparation of Nucleic Acid-Encoded Peptide and Protein Libraries for In Vitro Evolution Protocols [PDF]
, 2000 Markus Kurz, Guannan Kuang, Peter Lohse
openalex +2 more sources
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Electron microscopy mapping of oligopurine tracts in duplex DNA by peptide nucleic acid targeting [PDF]
, 1994 Vadim V. Demidov +7 more
openalex +1 more source
Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. [PDF]
, 1988 The major hepatitis B virus (HBV) core protein is a viral structural protein involved in nucleic acid binding. Its coding sequence contains an extension of 29 codons (the "precore" region) at the amino terminus of the protein which is present in a ...
Garcia, PD +3 more
core
Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials
Advanced Healthcare Materials, EarlyView.The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite +4 more
wiley +1 more source
Solid-phase synthesis of negatively charged pna decamer with GlyψL-Glu pseudopeptide bond.
Тонкие химические технологии, 2007 Solid-phase Boc-protocol and synthetic strategy of negatively charged peptide nucleic acids has been suggested. New thymine containing negatively charged PNA decamer based on L-glutamic acid and glycine was synthesized.
N. P. Boyarskaya +3 more
doaj
Molecular Therapy: Nucleic Acids, 2016 Staphylococcus aureus infections present a serious challenge to healthcare practitioners due to the emergence of resistance to numerous conventional antibiotics.
Mostafa FN Abushahba +2 more
doaj +1 more source
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses
Advanced Healthcare Materials, EarlyView.Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri +6 more
wiley +1 more source