Results 131 to 140 of about 690,671 (364)
Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid. [PDF]
, 1995 L.C. Boffa +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
International Journal of Medical Sciences, 2010 Progress in genome research led to new perspectives in diagnostic applications and to new promising therapies. On account of their specificity and sensitivity, nucleic acids (DNA/RNA) increasingly are in the focus of the scientific interest.
Manfred Wiessler, Waldemar Waldeck, Ruediger Pipkorn, Christian Kliem, Peter Lorenz, Heinz Fleischhacker, Manuel Hafner, Klaus Braun
doaj
In utero nanoparticle delivery for site-specific genome editing
Nature Communications, 2018 The correction of genetic defects in utero could allow for improved outcomes of gene therapy. Here, the authors demonstrate safe delivery of nanoparticles to fetal mouse tissues, and show that nanoparticles containing peptide nucleic acids to edit the ...
Adele S. Ricciardi +15 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2019 Streptococcus pyogenes is an exclusively human pathogen causing a wide range of clinical manifestations from mild superficial infections to severe, life-threatening, invasive diseases. S.
Gina Barkowsky +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall +14 more
wiley +1 more source
The molecular cloning and characterisation of cDNA coding for the alpha subunit of the acetylcholine receptor [PDF]
, 1982 The published version of this article is available at Oxford Journals in Nucleic Acids Research at http://nar.oxfordjournals.org/content/10/19/5809.full.pdf+htmlA rare cDNA coding for most of the α subunit of the Torpedo nicotinic acetylcholine receptor ...
Barnard, EA +5 more
core +1 more source
Information transfer from peptide nucleic acids to RNA by template- directed syntheses [PDF]
, 1997 Jürgen Schmidt
openalex +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Supporting data for the characterization of PNA–DNA four-way junctions
Data in Brief, 2015 Holliday or DNA four-way junctions (4WJs) are cruciform/bent structures composed of four DNA duplexes. 4WJs are key intermediates in homologous genetic recombination and double-strand break repair.
Douglas Iverson +5 more
doaj +1 more source