Results 151 to 160 of about 665,888 (285)

Peptide Nucleic Acids: On the Road to New Gene Therapeutic Drugs [PDF]

, 2000
Peter Nielsen
openalex   +1 more source

Recent Advancements in Development and Therapeutic Applications of Genome-Targeting Triplex-Forming Oligonucleotides and Peptide Nucleic Acids. [PDF]

Pharmaceutics, 2023
Mikame Y, Yamayoshi A.
europepmc   +1 more source

Targeted Delivery of Plasmid DNA to Myogenic Cells via Transferrin-Conjugated Peptide Nucleic Acid [PDF]

, 2000
Kenneth W. Liang, Eric P. Hoffman, Leaf Huang   +2 more
openalex   +1 more source

Relative Binding Free Energy Estimation of Congeneric Ligands and Macromolecular Mutants with the Alchemical Transfer with Coordinate Swapping Method [PDF]

arXiv
We present the Alchemical Transfer with Coordinate Swapping (ATS) method to enable the calculation of the relative binding free energies between large congeneric ligands and single-point mutant peptides to protein receptors with the Alchemical Transfer Method (ATM) framework.
arxiv  

Rapid detection of microorganisms by peptide nucleic acids [PDF]

, 2009
Peptide nucleic acid (PNA) molecules are DNA mimics, where the negatively charged sugarphosphate backbone is replaced by an achiral, neutral polyamide backbone formed by repetitive units of N–(2-aminoethyl) glycine.
Azevedo, N. F., Vieira, M. J.
core  

Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids. [PDF]

JACS Au, 2023
Zheng H, Clausse V, Amarasekara H, Mazur SJ, Botos I, Appella DH.   +5 more
europepmc   +1 more source

Control of electron transfer in DNA by peptide nucleic acids (PNA) [PDF]

, 2000
Kazuhito Tanabe, Kazushige Yoshida, Chikara Dohno, Akimitsu Okamoto, Isao Saito   +4 more
openalex   +1 more source

Killing two birds with one stone: a chemically plausible scheme for linked nucleic acid replication and coded peptide synthesis

, 1997
John D. Sutherland, Jonathan M. Blackburn   +1 more
openalex   +1 more source

Reflections on a Copenhagen–Minneapolis Axis in Bioorganic Chemistry

Molecules
The international peptide community rejoiced when one of its most distinguished members, Morten Meldal of Denmark, shared the 2022 Nobel Prize in Chemistry. In fact, the regiospecific solid-phase “copper(I)-catalyzed 1,3-dipolar cycloaddition of terminal
George Barany, Paul R. Hansen
doaj   +1 more source

Head-to-head comparison of in vitro and in vivo efficacy of pHLIP-conjugated anti-seed gamma peptide nucleic acids. [PDF]

Cell Rep Phys Sci, 2023
Dhuri K, Duran T, Chaudhuri B, Slack FJ, Vikram A, Glazer PM, Bahal R.   +6 more
europepmc   +1 more source