Results 191 to 200 of about 690,671 (364)

Enhanced Doxorubicin Cytotoxicity on Breast Cancer Spheroids by Aptamer Targeted Co‐Delivery with Hyaluronidase

open access: yesAdvanced Therapeutics, EarlyView.
Breast cancer is one of the most prevalent solid tumors in women. Doxorubicin is loaded mesoporous silica nanoparticles, capped with HER2‐specific aptamers, and the particle surface is functionalized with hyaluronidase. This dual‐functionalized nanocarrier system offers a promising solution for the drug resistance by solid tumors.
Murat Kavruk   +8 more
wiley   +1 more source

Nanoparticle-mediated genome editing in single-cell embryos via peptide nucleic acids. [PDF]

open access: yesBioeng Transl Med, 2023
Putman R   +6 more
europepmc   +1 more source

Peptide nucleic acids: Advanced tools for biomedical applications

open access: yesJournal of Biotechnology, 2017
Anjali Gupta, A. Mishra, N. Puri
semanticscholar   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

open access: yesAdvanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song   +9 more
wiley   +1 more source

Peptide Nucleic Acid Probe Detection of Mutations in Mycobacterium tuberculosis Genes Associated with Drug Resistance [PDF]

open access: gold, 2002
Larry E. Bockstahler   +6 more
openalex   +1 more source

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti‐MicroRNA Therapies

open access: yesAdvances in Materials, 2016
K. R. Beavers   +10 more
semanticscholar   +1 more source

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