Results 191 to 200 of about 719,118 (354)

Cationic Calix[4]arene Vectors to Efficiently Deliver AntimiRNA Peptide Nucleic Acids (PNAs) and miRNA Mimics. [PDF]

Pharmaceutics, 2023
Gasparello J, Papi C, Zurlo M, Volpi S, Gambari R, Corradini R, Casnati A, Sansone F, Finotti A.   +8 more
europepmc   +1 more source

Synthesis and DNA/RNA complementation studies of peptide nucleic acids containing 5-halouracils

, 2016
Chundong Liu, Jianhua Wang, Yang Xie, Hang Chen   +3 more
openalex   +2 more sources

Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo [PDF]

, 2005
Jeremy E. Wilusz
openalex   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

Advanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo, Xiaomeng Jia, Shenghong Wang, Xinyu Li, Yajing Liu, Lisen Lin, Zhengkun Wang, Fujun Liu, Slawomir Wolczynski, Nafis Rahman, Jie Gao, Xuguang Du, Suk‐Ying Tsang, Jiali Liu, Wei Song, Xiangdong Li   +15 more
wiley   +1 more source

Nanoparticle-mediated genome editing in single-cell embryos via peptide nucleic acids. [PDF]

Bioeng Transl Med, 2023
Putman R, Ricciardi AS, Carufe KEW, Quijano E, Bahal R, Glazer PM, Saltzman WM.   +6 more
europepmc   +1 more source

Peptide Nucleic Acids as Tools for Single-Molecule Sequence Detection and Manipulation

, 2011
Hagar Zohar, Craig L. Hetherington, Carlos Bustamante, Susan J. Muller   +3 more
openalex   +2 more sources

Transcription Factor Decoy Molecules Based on a Peptide Nucleic Acid (PNA)-DNA Chimera Mimicking Sp1 Binding Sites [PDF]

, 2003
Monica Borgatti, Ilaria Lampronti, Alessandra Romanelli, Carlo Pedone, Michele Saviano, Nicoletta Bianchi, Carlo Mischiati, Roberto Gambari   +7 more
openalex   +1 more source

Molecular self‐assembly using peptide nucleic acids

Biopolymers, 2017
Or Berger, E. Gazit
semanticscholar   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Synthesis of Bifacial Peptide Nucleic Acids with Diketopiperazine Backbones. [PDF]

Synlett, 2022
Devari S, Bhunia D, Bong D.
europepmc   +1 more source