Results 301 to 310 of about 719,118 (354)

Vancomycin‐Functionalized Nanodelivery Systems for Antibacterial Tissue Engineering Scaffolds

Advanced NanoBiomed Research, EarlyView.
This review consolidates recent advancements in VAN nanoformulations, critically evaluating their design principles, release mechanisms, and efficacy profiles against resistant Gram‐positive pathogens. While promising in vitro and in vivo results have been demonstrated, the clinicaltranslation of these technologies necessitates further rigorous ...
Nima Beheshtizadeh, Mahsa Mohammadzadeh, Amir Abbas Seraji, Ali Pirsadeghi, Elham Zendedel, Maliheh Gharibshahian   +5 more
wiley   +1 more source

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

Advanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza, Kimia Mozahheb Yousefi, Sara Minaeian   +2 more
wiley   +1 more source

Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials

Advanced NanoBiomed Research, EarlyView.
Black and violet phosphorus‐based biomaterials exhibit broad‐spectrum antibacterial efficacy in various infections, including bone, skin, ocular, dental, lung, and sepsis cases. Their antibacterial mechanisms include physical disruption, light‐driven effects, targeted drug delivery, and enhanced composite strategies.
Zhuo Dai, Yu Zhang, Xiaoye Li, Ao He, Qiang Li, Weijun Xiu, Yongbin Mou, Heng Dong, Meng Ding   +8 more
wiley   +1 more source

Emergent Chemical Reactivity and Complexity of RNA Condensates

Angewandte Chemie, EarlyView.
RNA condensates capable of substrate enrichment and catalysis modulate their environment. Could this start a catalytic selection loop or evolution? Abstract The RNA world hypothesis posits the existence of life‐like assemblies that consisted mostly of RNA.
Samuel Hauf, Ryo Nakamura, Barbara Cellini, Yohei Yokobayashi, Mirco Dindo   +4 more
wiley   +1 more source

Microcondensate‐Mediated Intracellular Infusion of mRNA Across the Plasma Membrane

Angewandte Chemie, EarlyView.
The delivery of mRNA without lipid nanoparticles remains challenging. FcB(L17E)3‐driven microcondensates with nucleic acids, aided by short ssDNA, enable coacervate formation, actin‐dependent cytosolic infusion, and in vivo protein expression, offering a potential platform for next‐generation mRNA therapeutics and vaccination.
Yoshimasa Kawaguchi, Ayumi Kikkawa, Seigo Kimura, Hiroshi Abe, Shiroh Futaki   +4 more
wiley   +1 more source

2D Assemblies Based on a Tetraphenylethylene D,L‐Cyclic Peptide Scaffold

Angewandte Chemie, EarlyView.
A new scaffold based on four nanotube‐forming cyclic peptide units attached to a tetraphenylethene (TPE) core with pH‐dependent self‐assembly that provides light‐emitting 2D nanosheets with controlled thickness is described. Abstract Two dimensional (2D) materials and aggregation‐induced emission (AIE) fluorophores have recently gained attention due to
Alfonso Bayón‐Fernández, Alba Torrón‐Celada, Alejandro Méndez‐Ardoy, Maëva Coste, David Delgado‐Gestoso, Sébastien Ulrich, Javier Montenegro, Juan R. Granja   +7 more
wiley   +1 more source

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Angewandte Chemie, EarlyView.
This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley   +1 more source

Detection of a Target Nucleic Acid by Ligation-Assisted Fluorescence Enhancement of a Peptide Nucleic Acid (Pna) Twin Probe Via Disulfide Binding

Yasuomi Ouchi, Koki Ishii, Yumiko Sato, Hajime Shigeto, Shohei Yamamura, Yoshiyuki Hakata, Takashi Ohtsuki, Mizuki Kitamatsu   +7 more
openalex   +1 more source

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Application strategies of peptide nucleic acids toward electrochemical nucleic acid sensors.

In Analysis, 2021
Peptide nucleic acids (PNAs) have attracted tremendous interest in the fabrication of highly sensitive electrochemical nucleic acid biosensors due to their higher stability and increased sensitivity than common DNA probes.
Qingteng Lai, Wei Chen, Yanke Zhang, Zhengchun Liu   +3 more
semanticscholar   +1 more source