Results 331 to 340 of about 719,118 (354)
Some of the next articles are maybe not open access.
Nucleobase Modified Peptide Nucleic Acid
Nucleosides, Nucleotides and Nucleic Acids, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
R H E, Hudson +3 more
openaire +2 more sources
ELECTROPHORESIS, 2019
AbstractA rapid, high resolution, and low sample consumption CZE method is developed for peptide nucleic acid (PNA) analysis for the first time. 30% v/v acetonitrile in PNA sample and 20% v/v acetonitrile in 50 mM borax‐boric acid (pH 8.7) as BGE were employed after optimization.
Xiaoqian Wang +3 more
openaire +2 more sources
AbstractA rapid, high resolution, and low sample consumption CZE method is developed for peptide nucleic acid (PNA) analysis for the first time. 30% v/v acetonitrile in PNA sample and 20% v/v acetonitrile in 50 mM borax‐boric acid (pH 8.7) as BGE were employed after optimization.
Xiaoqian Wang +3 more
openaire +2 more sources
Antisense Properties of Peptide Nucleic Acid
1998The hybridization properties of peptide nucleic acid (PNA) combined with its ease of synthesis and high chemical and biological stability rapidly made this molecule a very attractive lead compound for the development of antisense gene therapeutic drugs.
openaire +2 more sources
Nucleic Acid Independent Synthesis of Peptides
1981In this review we summarize some results on enzymatic peptide biosynthesis, the subject has been reviewed recently (Kurahashi 1974; Froyshov et al. 1978; Katz and Demain 1977; Laland et al. 1978; Vining and Wright 1977; Kleinkauf and Koischwitz 1978). We will extent the concepts of enzymatic peptide elongation reactions which we have summarized earlier
H, Kleinkauf, H, von Döhren
openaire +2 more sources
2007
Peptide nucleic acids (PNAs) can be conveniently delivered into cells in complex with DNA and cationic lipid. This advance enables researchers to test the hypothesis that PNAs offer advantages for recognition of DNA or RNA targets within cells. In this review, I describe the intracellular delivery of PNAs as DNA-PNA-cationic lipid complexes and discuss
openaire +1 more source
Peptide nucleic acids (PNAs) can be conveniently delivered into cells in complex with DNA and cationic lipid. This advance enables researchers to test the hypothesis that PNAs offer advantages for recognition of DNA or RNA targets within cells. In this review, I describe the intracellular delivery of PNAs as DNA-PNA-cationic lipid complexes and discuss
openaire +1 more source
Peptide nucleic acids as therapeutic agents
Current Opinion in Structural Biology, 1999Peptide nucleic acids (PNAs) have been around for more than seven years and it was hoped, at their introduction, that they would quickly enter the fields of antisense and antigene technology and drug development. Despite their extremely favorable hybridization and stability properties, as well as the encouraging antisense and antigene activity of PNA ...
openaire +2 more sources
Automated Synthesis of Peptide Nucleic Acids and Peptide Nucleic Acid–Peptide Conjugates
Analytical Biochemistry, 1999L D, Mayfield, D R, Corey
openaire +2 more sources
Peptide Nucleic Acids and the Origin of Life
Chemistry & Biodiversity, 2007AbstractThe possibilities of pseudo‐peptide‐DNA mimics like PNA (peptide nucleic acid) having a role for the prebiotic origin of life prior to an RNA world is discussed on the basis of literature data showing that this type of molecules might have formed on the primitive earth (or other places in the universe), as well as data indicating the ...
openaire +3 more sources
Recent advances on application of peptide nucleic acids as a bioreceptor in biosensors development
Trends in Analytical Chemistry (TrAC), 2019Arezoo Saadati +6 more
semanticscholar +1 more source