Results 81 to 90 of about 5,781 (240)

Towards a Radio-guided Surgery with $\beta^{-}$ Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

, 2014
A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the deployment of ...
BELLINI, Fabio, Bocci, Valerio, Chiodi, Giacomo, COLLAMATI, FRANCESCO, Cremonesi, Marta, DE LUCIA, Erika, FACCINI, Riccardo, Ferrari, Mahila E., Frallicciardi, Paola M., Grana, Chiara M., Marafini, Michela, Mattei, Ilaria, Morganti, Silvio, PATERA, Vincenzo, PEPE, ALESSANDRA, PIERSANTI, LUCA, PINCI, davide, Recchia, Luigi, RUSSOMANDO, ANDREA, SARTI, ALESSIO, SCIUBBA, Adalberto, SENZACQUA, MARTINA, SOLFAROLI CAMILLOCCI, ELENA, VOENA, Cecilia   +23 more
core   +1 more source

Accuracy and precision assessment for activity quantification in individualized dosimetry of 177Lu-DOTATATE therapy [PDF]

, 2017
Background: In order to obtain a reliable 177Lu-DOTATATE therapy dosimetry, it is crucial to acquire accurate and precise activity measurements with the radionuclide calibrator, the SPECT/CT camera, and the NaI(Tl) well counter. The aim of this study was
Flamen, Patrick, Guiot, Thomas, Karfis, Ioannis, Marin, Gwennaëlle, Vandenberghe, Stefaan, Vanderlinden, Bruno, Wimana, Zena   +6 more
core   +2 more sources

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

ChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh, Rupesh R. Kurhade, Abrar A. M. Siddiqui, Shaikh Shahbaz A. Majeed, Thomas J. Webster, Mohammad Intakhab Alam, Abdul Wasy Zia, Md. Faiyazuddin   +7 more
wiley   +1 more source

Accuracy and precision of few‐time‐points renal dosimetry for [177Lu]Lu‐PSMA‐617 therapy: Analysis with nonlinear mixed‐effects modeling

Medical Physics, Volume 53, Issue 1, January 2026.
Abstract Background Determination of time‐integrated activity (TIA) with a reduced number of imaging sessions is essential for minimizing patient burden and clinical workload in the dosimetry of [177Lu]Lu‐PSMA‐617. One approach to achieve this is by performing single‐time‐point (STP) dosimetry.
Assyifa R. Hakim, Deni Hardiansyah, Elham Yousefzadeh‐Nowshahr, Ursula Nemer, Rien Ritawidya, Felix Kind, Ambros J. Beer, Philipp T. Meyer, Gerhard Glatting, Michael Mix   +9 more
wiley   +1 more source

177Lu-DOTATATE therapy in metastatic/ inoperable pheochromocytoma-paraganglioma

Endocrine Connections, 2020
Introduction: 177Lu-DOTATATE-based peptide receptor radionuclide therapy (PRRT) is a promising therapy for metastatic and/or inoperable pheochromocytoma and paraganglioma (PPGL).
Sanjeet Kumar Jaiswal, Vijaya Sarathi, Saba Samad Memon, Robin Garg, Gaurav Malhotra, Priyanka Verma, Ravikumar Shah, Manjeet Kaur Sehemby, Virendra A Patil, Swati Jadhav, Anurag Ranjan Lila, Nalini S Shah, Tushar R Bandgar   +12 more
doaj   +1 more source

Effect of image registration on 3D absorbed dose calculations in 177 Lu-DOTATOC Peptide Receptor Radionuclide Therapy [PDF]

, 2018
Peptide receptor radionuclide therapy (PRRT) is an effective MRT (molecular radiotherapy) treatment, which consists of multiple administrations of a radiopharmaceutical labelled with 177Lu or 90Y.
Berenato, Salvatore, Braglia, Luca, Ferri, Valentina, Filice, Angelina, Fioroni, Federica, Grassi, Elisa, Iori, Mauro, Patterson, Nick, Spezi, Emiliano, Versari, Annibale   +9 more
core   +2 more sources

Systematic review and meta‐analysis of the efficacy and safety of [177Lu]Lu‐edotreotide ([177Lu]Lu‐DOTATOC) for the treatment of neuroendocrine tumors

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract [177Lu]Lu‐edotreotide is a radiopharmaceutical therapy (RPT) targeting somatostatin receptors, which are commonly overexpressed on neuroendocrine tumors (NETs). This systematic literature review and meta‐analysis describes the efficacy and safety of [177Lu]Lu‐edotreotide in patients with NETs.
Richard P. Baum, Julia G. Fricke, Tristan Ruhwedel, Holger Amthauer, Erika Patricia Azorin‐Vega, Dieter Hörsch, Riccardo Laudicella, Vikalp Maheshwari, Martin A. Walter, Berna Degirmenci Polack, Simon F. Spiegl, Guillaume P. Nicolas   +11 more
wiley   +1 more source

Advanced metastatic pancreatic neuroendocrine tumor treated successfully with peptide receptor radionuclide therapy: a case report

Exploration of Targeted Anti-tumor Therapy, 2022
Neuroendocrine tumor (NET) is a rare tumor that has been observed in different sites such as lungs and throughout the gastrointestinal tract. Clinical features are usually non-specific and vary considerably depending upon the location of the tumor ...
Amit Kumar, Shweta Tanwar, Sudhish Gupta, Rajesh Chetiwal, Rohit Kumar   +4 more
doaj   +1 more source

The treatment of hyperinsulinemic hypoglycaemia in adults: an update [PDF]

, 2016
Treatment of hyperinsulinemic hypoglycaemia (HH) is challenging due to the rarity of this condition and the difficulty of differential diagnosis.
A. Colao, A. Faggiano, A. Pia, G. Pizza, M. V. Davi′, null null, V. Guarnotta   +6 more
core   +1 more source

Necrolytic Migratory Erythema as the First Manifestation of Functional Conversion in a Glucagonoma: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Necrolytic migratory erythema is a characteristic but often underrecognized manifestation of glucagonoma. Its timely identification can lead to early diagnosis and curative surgery of pancreatic neuroendocrine tumors that initially present as clinically silent lesions.
Matheus Felipe Ferreira Aguiar, Jose Jukemura   +1 more
wiley   +1 more source