Results 201 to 210 of about 939,420 (304)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Evaluation of the safety and immunogenicity of a peptide vaccine against canine leishmaniosis: a double-blind, multicenter, controlled clinical trial in dogs. [PDF]

Vet Q
Hurtado-Morillas C, Mas A, Orden JA, de Urbina-Fuentes L, Blanco MM, Domínguez-Bernal G, Martínez-Rodrigo A.   +6 more
europepmc   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Single dose of foot-and-mouth disease peptide vaccine fully protects swine and achieves intraserotype crossed neutralization. [PDF]

NPJ Vaccines
Blanco E, Torres E, de León P, Forner M, Bustos MJ, Hammer SE, Sobrino F, Andreu D, Defaus S.   +8 more
europepmc   +1 more source

Effects of Lactic Acid Bacteria and Yeasts on Growth Performance, Intestinal Health, and Organ Morphometry of Broiler Chickens

Food Safety and Health, EarlyView.
The fermentation of molasses‐vinasse with lactic acid bacteria and yeasts improves growth, intestinal health, digestive, and immune organs in chickens, promoting their productive performance and organic development. ABSTRACT This study evaluated the probiotic effects of lactic acid bacteria and yeasts on productive parameters, intestinal health, and ...
José Miranda‐Yuquilema, Fabian Astudillo‐Riera, Juan Taboada‐Pico, Mercy Cuenca‐Condo, Kevin Astudillo‐Vallejo   +4 more
wiley   +1 more source

Development of an efficacious oral peptide vaccine against infection with the carcinogenic liver fluke Opisthorchis viverrini. [PDF]

Vaccine
Phumrattanaprapin W, Shalash AO, Skwarczynski M, Smout MJ, Laha T, Toth I, Loukas A.   +6 more
europepmc   +1 more source

Peptide Vaccine [PDF]

, 2020
openaire   +1 more source

AGS-v PLUS, a Mosquito Salivary Peptide Vaccine, Modulates the Response to <i>Aedes</i> Mosquito Bites in Humans. [PDF]

Vaccines (Basel)
Barningham L, Carr IM, Jossi S, Cole M, Ponce A, Short M, Meneses C, Lacsina JR, Valenzuela JG, Oliveira F, Laurens MB, Friedman-Klabanoff DJ, Pleguezuelos O, Stead LF, McKimmie CS.   +14 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Yeast Display Reveals Plentiful Mutations That Improve Fusion Peptide Vaccine-Elicited Antibodies Beyond 59% HIV-1 Neutralization Breadth. [PDF]

Vaccines (Basel)
França CT, Pletnev S, Madan B, Katsamba PS, McKee K, Morano NC, Zhang B, Bahna F, Bylund T, Lin BC, Louder MK, Mannepalli S, Nimrania R, O'Dell S, Doria-Rose NA, Kwong PD, Shapiro L, Sheng Z, Zhou T, DeKosky BJ.   +19 more
europepmc   +1 more source