Results 171 to 180 of about 2,785,119 (387)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Antifatigue Effect and Peptide Sequence of Oligopeptides Derived from Yellow Chicken

Shipin gongye ke-ji
This study focused on oligopeptides derived from yellow chicken as the research object, aiming to investigate their antifatigue activity and potential functional peptide sequences.
Miao LI, Jiefang FENG, Yurong MA, Xianjun ZENG, Penglei CUI, Xuefei YE, Liang CHEN, Yuxin YANG, Ting LIU, Lei FANG   +9 more
doaj   +1 more source

Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus

, 2007
John J. Dwyer, Karen L. Wilson, Donna K. Davison, Stephanie A. Freel, Jennifer E. Seedorff, Stephen A. Wring, Nicolai A. Tvermoes, Thomas J. Matthews, Michael Greenberg, Mary K. Delmedico   +9 more
openalex   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Peptides binding peptides [PDF]

Nature Biotechnology, 2000
openaire   +2 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

Proceedings of the National Academy of Sciences of the United States of America, 1998
L. Lecea, T. Kilduff, C. Peyron, Xiao-Bing Gao, P. E. Foye, P. Danielson, C. Fukuhara, E. Battenberg, V. Gautvik, F. S. Bartlett, W. Frankel, A. Pol, F. Bloom, K. Gautvik, J. Sutcliffe   +14 more
semanticscholar   +1 more source

Vivo-Morpholinos: A Non-Peptide Transporter Delivers Morpholinos into a Wide Array of Mouse Tissues

, 2008
Paul A. Morcos, Yongfu Li, Shan Jiang
openalex   +1 more source

A Synthetic Peptide CTL Vaccine Targeting Nucleocapsid Confers Protection from SARS-CoV-2 Challenge in Rhesus Macaques [PDF]

, 2021
Paul E. Harris, Trevor Brasel, Christopher Massey, C.v. Herst, Scott Burkholz, Peter Lloyd, Tikoes Blankenberg, Thomas M. Bey, Richard T. Carback, Thomas Hodge, Serban Ciotlos, Lu Wang, Jason E. Comer, Reid Rubsamen   +13 more
openalex   +1 more source