Results 21 to 30 of about 1,056,473 (318)

Mechanisms of Antimicrobial Peptides from Bagasse against Human Pathogenic Bacteria

, 2023
Nonedible agricultural wastes (agricultural wastes, agro-industrial wastes, and fishery wastes) were chosen as potential sources of antimicrobial peptides and evaluated for antibacterial efficiency against human pathogens.
Narumon Phaonakrob, Sittiruk Roytrakul, Thitiporn Ditsawanon   +2 more
core   +1 more source

Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P^®)

Molecules, 2023
The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone, Dario Corbisiero, Paolo Cantelmi, Giulia Martelli, Chiara Palladino, Alessandra Tolomelli, Walter Cabri, Lucia Ferrazzano   +7 more
doaj   +1 more source

Blapstin, a Diapause-Specific Peptide-Like Peptide from the Chinese Medicinal Beetle Blaps rhynchopetera, Has Antifungal Function

Microbiology Spectrum, 2023
Drug resistance against bacteria and fungi has become common in recent years, and it is urgent to discover novel antimicrobial peptides to manage this problem.
La-Mei Zhang, Min Yang, Sheng-Wen Zhou, Hao Zhang, Ying Feng, Lei Shi, Dong-Sheng Li, Qiu-Min Lu, Zhong-He Zhang, Min Zhao   +9 more
doaj   +1 more source

The functional interaction between abaecin and pore-forming peptides indicates a general mechanism of antibacterial potentiation

, 2022
1723Long-chain proline-rich antimicrobial peptides such as bumblebee abaecin show minimal activity against Gram-negative bacteria despite binding efficiently to specific intracellular targets.
Vilcinskas, A., Cytrynska, M., Zdybicka-Barabas, A., Rahnamaeian, M.   +3 more
core   +1 more source

Bv8-Like Toxin from the Frog Venom of Amolops jingdongensis Promotes Wound Healing via the Interleukin-1 Signaling Pathway

Toxins, 2019
Prokineticins are highly conserved small peptides family expressed in all vertebrates, which contain a wide spectrum of functions. In this study, a prokineticin homolog (Bv8-AJ) isolated from the venom of frog Amolops jingdongensis was fully ...
Jiajia Chang, Xiaoqin He, Jingmei Hu, Peter Muiruri Kamau, Ren Lai, Dingqi Rao, Lei Luo   +6 more
doaj   +1 more source

Meta-Analysis of Diagnostic Performance of Contrast-Fractional Flow Reserve versus Quantitative Flow Ratio for Functional Assessment of Coronary Stenoses

Journal of Interventional Cardiology, 2020
Background. Use of the fractional flow reserve (FFR) technique is recommended to evaluate coronary stenosis severity and guide revascularization. However, its high cost, time to administer, and the side effects of adenosine reduce its clinical utility ...
Ruitao Zhang, Jianwei Zhang, Lijun Guo
doaj   +1 more source

Peptide Stapling Applied to Antimicrobial Peptides

Antibiotics, 2023
Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço, Thuanny Borba Rios, Állan Pires da Silva, Octávio Luiz Franco, Marcelo Henrique Soller Ramada   +4 more
openaire   +3 more sources

Synthetic Antimicrobial Immunomodulatory Peptides: Ongoing Studies and Clinical Trials

, 2022
The increasingly widespread antimicrobial resistance forces the search for new antimicrobial substances capable of fighting infection. Antimicrobial peptides (AMPs) and their synthetic analogs form an extensive group of compounds of great structural ...
Katarzyna E. Greber, Paduszyńska, Małgorzata, Greber, Katarzyna E., Małgorzata Lesiuk, Małgorzata Paduszyńska, Lesiuk, Małgorzata   +5 more
core   +1 more source

Structure-Activity Relationship Investigations of Novel Constrained Chimeric Peptidomimetics of SOCS3 Protein Targeting JAK2

Pharmaceuticals, 2022
SOCS3 (suppressor of cytokine signaling 3) protein suppresses cytokine-induced inflammation and its deletion in neurons or immune cells increases the pathological growth of blood vessels. Recently, we designed several SOCS3 peptidomimetics by assuming as
Sara La Manna, Marilisa Leone, Flavia Anna Mercurio, Daniele Florio, Daniela Marasco   +4 more
doaj   +1 more source

Chemical composition and biological activity of seed oil of amaranth varieties

Nova Biotechnologica et Chimica, 2018
The work is devoted to study of seed oil composition of amaranth varieties: Kharkov, Lera, Andijan and Helios, acclimatized in Uzbekistan. We demonstrated the possibility of using reversed-phase HPLC using a refractometric detector, which allows ...
Bozorov Soyibjon S., Berdiev Nodir Sh., Ishimov Uchkun J., Olimjonov Shukhratjon S., Ziyavitdinov Jamolitdin F., Asrorov Akmal M., Salikhov Shavkat I.   +6 more
doaj   +1 more source