Results 31 to 40 of about 1,146,906 (315)

Bv8-Like Toxin from the Frog Venom of Amolops jingdongensis Promotes Wound Healing via the Interleukin-1 Signaling Pathway

Toxins, 2019
Prokineticins are highly conserved small peptides family expressed in all vertebrates, which contain a wide spectrum of functions. In this study, a prokineticin homolog (Bv8-AJ) isolated from the venom of frog Amolops jingdongensis was fully ...
Jiajia Chang, Xiaoqin He, Jingmei Hu, Peter Muiruri Kamau, Ren Lai, Dingqi Rao, Lei Luo   +6 more
doaj   +1 more source

Blapstin, a Diapause-Specific Peptide-Like Peptide from the Chinese Medicinal Beetle Blaps rhynchopetera, Has Antifungal Function

Microbiology Spectrum, 2023
Drug resistance against bacteria and fungi has become common in recent years, and it is urgent to discover novel antimicrobial peptides to manage this problem.
La-Mei Zhang, Min Yang, Sheng-Wen Zhou, Hao Zhang, Ying Feng, Lei Shi, Dong-Sheng Li, Qiu-Min Lu, Zhong-He Zhang, Min Zhao   +9 more
doaj   +1 more source

The functional interaction between abaecin and pore-forming peptides indicates a general mechanism of antibacterial potentiation

, 2022
1723Long-chain proline-rich antimicrobial peptides such as bumblebee abaecin show minimal activity against Gram-negative bacteria despite binding efficiently to specific intracellular targets.
Vilcinskas, A., Cytrynska, M., Zdybicka-Barabas, A., Rahnamaeian, M.   +3 more
core   +1 more source

Meta-Analysis of Diagnostic Performance of Contrast-Fractional Flow Reserve versus Quantitative Flow Ratio for Functional Assessment of Coronary Stenoses

Journal of Interventional Cardiology, 2020
Background. Use of the fractional flow reserve (FFR) technique is recommended to evaluate coronary stenosis severity and guide revascularization. However, its high cost, time to administer, and the side effects of adenosine reduce its clinical utility ...
Ruitao Zhang, Jianwei Zhang, Lijun Guo
doaj   +1 more source

Synthetic Antimicrobial Immunomodulatory Peptides: Ongoing Studies and Clinical Trials

, 2022
The increasingly widespread antimicrobial resistance forces the search for new antimicrobial substances capable of fighting infection. Antimicrobial peptides (AMPs) and their synthetic analogs form an extensive group of compounds of great structural ...
Katarzyna E. Greber, Paduszyńska, Małgorzata, Greber, Katarzyna E., Małgorzata Lesiuk, Małgorzata Paduszyńska, Lesiuk, Małgorzata   +5 more
core   +1 more source

Structure-Activity Relationship Investigations of Novel Constrained Chimeric Peptidomimetics of SOCS3 Protein Targeting JAK2

Pharmaceuticals, 2022
SOCS3 (suppressor of cytokine signaling 3) protein suppresses cytokine-induced inflammation and its deletion in neurons or immune cells increases the pathological growth of blood vessels. Recently, we designed several SOCS3 peptidomimetics by assuming as
Sara La Manna, Marilisa Leone, Flavia Anna Mercurio, Daniele Florio, Daniela Marasco   +4 more
doaj   +1 more source

Chemical composition and biological activity of seed oil of amaranth varieties

Nova Biotechnologica et Chimica, 2018
The work is devoted to study of seed oil composition of amaranth varieties: Kharkov, Lera, Andijan and Helios, acclimatized in Uzbekistan. We demonstrated the possibility of using reversed-phase HPLC using a refractometric detector, which allows ...
Bozorov Soyibjon S., Berdiev Nodir Sh., Ishimov Uchkun J., Olimjonov Shukhratjon S., Ziyavitdinov Jamolitdin F., Asrorov Akmal M., Salikhov Shavkat I.   +6 more
doaj   +1 more source

Selection of experimental animals and modeling methods in developmental dysplasia of the hip research

EFORT Open Reviews
Developmental dysplasia of the hip (DDH) is a common neonatal musculoskeletal condition characterized by hip instability and inadequate acetabular coverage. If untreated, it can lead to osteoarthritis, chronic pain, and eventual hip replacement.
Yu Rao, Gonzalo Saiz-Gonzalo, Prateeksha Prateeksha, Anmin Wang, Hongxin Shi, Weiguo Wang, Chuan Li   +6 more
doaj   +1 more source

Isolation and proteomic characterization of tropomyosin extracted from edible insect protein

Food Chemistry: Molecular Sciences, 2021
Edible insects are considered promising sustainable protein sources. Thermal treatments and proteolysis are commonly used to improve their safety and quality. However, their allergenicity remains mostly unexplored.
Felicia G. Hall, Andrea M. Liceaga
doaj   +1 more source

Peptides, Antibodies, Peptide Antibodies and More [PDF]

International Journal of Molecular Sciences, 2019
The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire   +3 more sources