Results 81 to 90 of about 1,146,906 (315)

Lasso peptides realm: insights and applications

Lasso peptides exhibit a range of bioactivities, including antiviral effects, inhibition of the glucagon receptor, blockade of the endothelin type B receptor, inhibition of myosin light chain kinase, and modulation of the atrial natriuretic factor, as ...
Musaimi, Othman Al
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Peptide Bioinformatics- Peptide Classification Using Peptide Machines [PDF]

, 2008
Peptides scanned from whole protein sequences are the core information for many peptide bioinformatics research such as functional site prediction, protein structure identification, and protein function recognition. In these applications, we normally need to assign a peptide to one of the given categories using a computer model.
openaire   +2 more sources

10-mer and 9-mer WALK Peptides with Both Antibacterial and Anti-Inflammatory Activities

, 2022
Natural antimicrobial peptides (AMPs) are multifunctional host defense peptides (HDPs) that are valuable for various therapeutic applications. In particular, natural and artificial AMPs with dual antibacterial immunomodulatory functions emerged as ...
Sung-Hee Lee, Kim, Su-Jin, Lee, Sung-Hee, Ji-Hun Kim, Won, Hyung-Sik, Kang, Tae-Bong, Lee, Sang-Hyuck, Jae-Won Park, Kweon, Hyuk-Jung, Sang-Hyuck Lee, Beom-Jun Kim, Keum, Minho, Su-Jin Kim, Dong-Hyuk Kim, Hyung-Sik Won, Jihoon Kim, Hyuk-Jung Kweon, Kim, Jihoon, Park, Jae-Won, Kim, Beom-Jun, Kim, Ji-Hun, Kim, Dong-Hyuk, Tae-Bong Kang, Minho Keum   +23 more
core   +1 more source

The Small Key to the Treasure Chest: Endogenous Plant Peptides Involved in Symbiotic Interactions

Plants
Plant growth and development are inextricably connected with rhizosphere organisms. Plants have to balance between strong defenses against pathogens while modulating their immune responses to recruit beneficial organisms such as bacteria and fungi.
Anna Mamaeva, Arina Makeeva, Daria Ganaeva   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Crustacean Bioactive Peptides

, 2013
Research on crustacean peptides has concentrated mainly on decapods and isopods, and a growing number of >200 peptides have been sequenced from these two groups, the majority from decapods, but recently, the annotation of the Daphnia pulexgenome has ...
Dircksen, Heinrich,, H. Dircksen
core   +1 more source

Synthetic receptors for the differentiation of phosphorylated peptides and synthesis and use of tetrahydrofuran amino acids [PDF]

, 2010
In the first part of the work a combination of bis(Zn(II)-cyclen) triazine metal complex binding sites with guanidinium moieties or Zn(II)-NTA complexes leads to artificial receptors for the differentiation of phosphorylated peptides which contain either
Grauer, Andreas
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Immunogold Staining Procedure for the Localisation of Regulatory Peptides

, 1982
The use of protein A- and IgG-conjugated colloidal gold staining methods for the immuno-localisation of peptide hormones and neurotransmitters at light - and electron microscope level are described and discussed. Bright-field and dark-ground illumination
Varndell, I.M., De Mey, J., Buchan, A. M. J., Probert, L., Polak, J. M., Bloom, S. R., Gu, Jiang, Tapia, Félix J.   +7 more
core