Three‐dimensional stem cell‐derived organoid model can serve as a robust platform to study the underlying molecular mechanisms of UFs, UFs health disparity, environmental risk factors, besides offering invaluable insights for potential therapeutic interventions.
Mervat M. Omran+9 more
wiley +1 more source
Mutation- and Transcription-Driven Omic Burden of Daptomycin/Dalbavancin-R and Glycopeptide-RS Fitness Costs in High-Risk MRSA: A Nexus in Antimicrobial Resistance Mechanisms-Genome Proneness-Compensatory Adaptations. [PDF]
Chines E+4 more
europepmc +1 more source
Protective immune response against Rhodococcus equi: An innate immunity‐focused review
Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira+4 more
wiley +1 more source
Horizontal Transfer of Bacterial Operons into Eukaryote Genomes. [PDF]
Kogay R, Wolf YI, Koonin EV.
europepmc +1 more source
Protein import into bacterial endosymbionts and evolving organelles
The acquisition of bacterial endosymbionts by ancient host cells followed by massive adaptation of the partners gave rise to mitochondria and plastids. Today, various systems with younger and less integrated endosymbionts provide insights into the initial steps in the endosymbiont to organelle transition.
Megan E. S. Sørensen+3 more
wiley +1 more source
Berberine inhibits the tarO gene to impact MRSA cell wall synthesis. [PDF]
Gu X+9 more
europepmc +1 more source
N‐acetylglucosamine sensing in the filamentous soil fungus Trichoderma reesei
N‐acetylglucosamine (GlcNAc) is involved in diverse signaling pathways in dimorphic yeasts and bacteria, including virulence and cell death. Here, we investigated GlcNAc sensing in Trichoderma reesei. GlcNAc signaling influences around 2100 genes in this filamentous soil fungus.
Sadia Fida Ullah+6 more
wiley +1 more source
<i>Lactobacilli</i>-Mediated Regulation of the Microbial-Immune Axis: A Review of Key Mechanisms, Influencing Factors, and Application Prospects. [PDF]
Ji HF+7 more
europepmc +1 more source
d‐amino acids: new functional insights
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni+5 more
wiley +1 more source
Phage Endolysins as Promising and Effective Candidates for Use Against Uropathogenic <i>Escherichia coli</i>. [PDF]
Wesołowski W+8 more
europepmc +1 more source