Metabolites Isolated from <i>Senecio nutans</i> Sch. Bip and Their Synthesized Oximes Inhibit Angiotensin I-Converting Enzyme Activity in Vascular Smooth Muscle. [PDF]
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Peptidyl dipeptidase in rabbit brain microvessels
Biochimica Et Biophysica Acta - Biomembranes, 1978The activity of peptidyl dipeptidase (peptidyldipeptide hydrolase, EC 3.4.15.1), also known as angiotensin-converting enzyme, was studied in small blood vessel preparations isolated from rabbit brain. The vascular preparation contained arterioles and capillaries and was essentially free of extravascular material.
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Hydrolysis of enkephalin by cultured human endothelial cells and by purified peptidyl dipeptidase
Biochemical Pharmacology, 1978Abstract : The experiments indicate that rapid inactivation of enkephalins may be due to at least two different enzymes present in tissues. A peptidyl dipeptidase which is a component of plasma membrane of various cells may degrade enkephalins by liberating a C-terminal dipeptide and an aminopeptidase in endothelial cells may cleave peptides, that they
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