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Ribosomal Components of the Peptidyl Transferase Center
1984The past years have seen tremendous progress in our knowledge of the structures of ribosomal proteins and RNA (for review articles see Wittmann 1983; Noller 1984, Wollenzien et al. 1984). Yet our understanding of the ribosomal mechanisms has remained rather fragmentary.
E. Küchler, G. Steiner, A. Barta
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Isomers of Aminoacyl- and Peptidyl-tRNA in the Peptidyl Transferase Reaction
1986The synthesis of the peptide bonds takes place via the transfer of the activated peptidyl residue from peptidyl-tRNA to the aminoacyl residue of aa-tRNA. Although the ester bond of charged tRNAs is an energy-rich bond with the free energy of hydrolysis approximately equal to the free energy of hydrolysis of ATP (Loftfield, 1972), the reaction between ...
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Identifying the peptidyl transferase centre
Trends in Biochemical Sciences, 1982R.A. Garrett, Paul Wooley
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