Results 221 to 230 of about 163,491 (263)

Ribosomal Components of the Peptidyl Transferase Center

1984
The past years have seen tremendous progress in our knowledge of the structures of ribosomal proteins and RNA (for review articles see Wittmann 1983; Noller 1984, Wollenzien et al. 1984). Yet our understanding of the ribosomal mechanisms has remained rather fragmentary.
E. Küchler, G. Steiner, A. Barta
openaire   +1 more source

Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.

Angewandte Chemie, 2016
M. Fonvielle, Nicolas Sakkas, L. Iannazzo, Chloé Le Fournis, D. Patin, D. Mengin-Lecreulx, A. El-Sagheer, E. Braud, Sébastien Cardon, T. Brown, M. Arthur, M. Ethève-Quelquejeu   +11 more
semanticscholar   +1 more source

Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Phosphopantetheinyl Transferases.

Bioconjugate chemistry, 2015
J. Grünewald, H. Klock, Susan E. Cellitti, B. Bursulaya, D. Mcmullan, David H. Jones, Hsien‐Po Chiu, Xing Wang, Paula Patterson, Huanfang Zhou, Julie Vance, Edward Nigoghossian, Hung Tong, D. Daniel, W. Mallet, Weijia Ou, T. Uno, Ansgar Brock, S. Lesley, B. Geierstanger   +19 more
semanticscholar   +1 more source

Two classes of inhibitors of peptidyl transferase activity in eukaryotes

Nature, 1974
THE 12,13-epoxytrichothecenes (Fig. 1) form a group of fungal toxins with a tricyclic trichothecene ring system. (For review, see ref. 1). They have been shown to inhibit protein synthesis in a variety of eukaryotic systems2 and in particular they block peptidyl transferase activity as determined by the puromycin-fragment reaction3. More recent studies
openaire   +2 more sources

Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases.

Biochemistry, 1998
L. Quadri, P. Weinreb, Ming Lei, M. Nakano, P. Zuber, C. Walsh   +5 more
semanticscholar   +1 more source

Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism.

Biochemistry, 2004
M. Mofid, Robert Finking, L. Essen, M. Marahiel   +3 more
semanticscholar   +1 more source

Chapter 10 using phosphopantetheinyl transferases for enzyme posttranslational activation, site specific protein labeling and identification of natural product biosynthetic gene clusters from bacterial genomes.

Methods in Enzymology, 2009
Murat Sunbul, Keya Zhang, Jun Yin
semanticscholar   +1 more source

Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognition.

Biochemistry, 2004
Robert Finking, M. Mofid, M. Marahiel
semanticscholar   +1 more source

Ribozyme-catalysed amino-acid transfer reactions

Nature, 1996
P. Lohse, J. Szostak
semanticscholar   +1 more source

The npgA/cfwA gene encodes a putative 4'-phosphopantetheinyl transferase which is essential for penicillin biosynthesis in Aspergillus nidulans

Current Genetics, 2003
D. Keszenman-Pereyra, S. Lawrence, Mohammed-Elfatih Twfieg, J. Price, G. Turner   +4 more
semanticscholar   +1 more source