Results 141 to 150 of about 1,668 (171)

Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca<sup>2+</sup> dependent allosteric binding site. [PDF]

open access: yesNat Commun
Dakin LA   +25 more
europepmc   +1 more source

Citrullination negatively regulates the functions of the p53 protein and opposes its ubiquitination and degradation. [PDF]

open access: yesProc Natl Acad Sci U S A
Yang YF   +10 more
europepmc   +1 more source

Peptidylarginine deiminase 4 deficiency alleviates hypoxia/reoxygenation-induced cardiomyocyte injury. [PDF]

open access: yesPLoS One
Mand M   +6 more
europepmc   +1 more source

Cardiac PAD2 expression and myocardial citrullination decline with age in female mice independent of estrogen. [PDF]

open access: yesAm J Physiol Heart Circ Physiol
Shorthill SK   +10 more
europepmc   +1 more source

Current knowledge into the role of the peptidylarginine deiminase (PAD) enzyme family in cardiovascular disease

European Journal of Pharmacology, 2021
Peptidylarginine deiminase (PAD) family members have a vital role in maintaining the stability of the extracellular matrix (ECM) during remodelling in several heart diseases. PAD-mediated deamination, or citrullination, has been studied in different physiological and pathological conditions in the body.
Doa'A G F Al-U'Datt   +2 more
exaly   +3 more sources

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