Results 201 to 210 of about 11,623 (233)

Broad-Spectrum Antiviral Activity of Cyclophilin Inhibitors Against Coronaviruses: A Systematic Review. [PDF]

open access: yesInt J Mol Sci
Elhabyan A   +8 more
europepmc   +1 more source

VEPTP inhibition with an extracellular domain targeting antibody did not restore albuminuria in a mouse model of diabetic kidney disease. [PDF]

open access: yesPhysiol Rep
Rana R   +11 more
europepmc   +1 more source
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Possible involvement of peptidylprolyl isomerase Pin1 in rheumatoid arthritis

Pathology International, 2010
The peptidylprolyl isomerase Pin1 is over‐expressed in some human diseases including malignancies and chronic inflammatory diseases, this suggests that it contributes to the constitutive activation of certain intracellular signaling pathways that promote cell proliferation and cell invasion.
Akiko, Nagaoka   +7 more
openaire   +2 more sources

Peptidylprolyl Cis / Trans Isomerases (Immunophilins): Biological Diversity - Targets - Functions

Current Topics in Medicinal Chemistry, 2003
Information recovered from genome sequencing projects, multiple sequence alignments, structural analyses of PPIase and published records were used in deciphering the biological diversity, functions and targets of four groups of proteins encoded by dissimilar sets of sequences whose spatial representations exhibit peptidylprolyl cis/trans isomerase ...
openaire   +2 more sources

Peptidylprolyl cistrans isomerases of Legionella pneumophila: virulence, moonlighting and novel therapeutic targets

Biochemical Society Transactions, 2014
Legionella pneumophila, typically a parasite of free-living protozoa, can also replicate in human alveolar macrophages and lung epithelial cells causing Legionnaires’ disease in humans, a severe atypical pneumonia. The pathogen encodes six peptidylprolyl cis–trans isomerases (PPIases), which generally accelerate folding of prolyl peptide bonds, and ...
Janine, Rasch   +2 more
openaire   +2 more sources

Peptidylprolyl cis/trans isomerase activity and molecular evolution of vertebrate Cyclophilin A.

Yi chuan = Hereditas, 2017
Peptidylprolyl isomerases (PPIase) cyclophilin A (CypA, encoded by PPIA) is a typical member of the Cyclophilin family and is involved in protein folding/translocation, signal transduction, inflammation, immune system regulation, apoptosis and virus replication.
Li-qian, Ren   +4 more
openaire   +1 more source

Peptidylprolyl isomerase D circular RNA sensitizes breast cancer to trastuzumab through remodeling HER2 N4-acetylcytidine modification

Journal of Applied Genetics
Human epidermal growth factor receptor 2 (HER2) overexpression and activation are crucial for trastuzumab resistance in HER2-positive breast cancer; however, the potential regulatory mechanism of HER2 is still largely undetermined. In this study, a novel circular RNA derived from peptidylprolyl isomerase D (PPID) is identified as a negative regulator ...
Shengting, Wang   +7 more
openaire   +2 more sources

Small Molecule Inhibitors of Peptidylprolyl cis/trans Isomerase

Current Enzyme Inhibition, 2010
Tadashi Mori, Takafumi Uchida
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce   +2 more
exaly  

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