Results 91 to 100 of about 1,975,266 (317)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Future of fishing for a vulnerable atoll: trends in catch and catch-per-unit-effort in Tokelau's domestic marine fisheries 1950-2016 [PDF]

open access: yes, 2018
Tokelau is among the most vulnerable countries to climate change from both an environmental and economic perspective, whilst being highly dependent on marine resources for dietary nutrition.
Amy Coghlan (14734027)   +5 more
core  

PB2262: PEGFILGRASTIM IN THE SUPPORTIVE CARE OF HEAVILY PRETREATED MULTIPLE MYELOMA IN POMALIDOMIDE-BASED TREATMENT

open access: yesHemaSphere, 2022
C. Cerchione   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Unit-pricing: Minimising Christchurch Domestic Waste [PDF]

open access: yes
One economic tool that can aid in the achievement of waste minimisation targets is unit-pricing. Unit-pricing in the waste management sector refers to a pricing system that charges households for their collection and disposal service relative to the ...
Tait, Peter R.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Chemotherapy and palliative care near end-of life: examining the appropriateness at a cancer institute for colorectal cancer patients

open access: yesBMC Palliative Care, 2018
Background Appropriate cessation of chemotherapy and timely referral of patients to hospice services are crucial for the quality of care near death. We investigated the quality of care in our Cancer Institute in very advanced metastatic colorectal cancer
Ilaria Massa   +13 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Unit-root and stationarity testing with empirical application on industrial production of CEE-4 countries [PDF]

open access: yes
The purpose of this paper is to explain both the need and the procedures of unit-root testing to a wider audience. The topic of stationarity testing in general and unit root testing in particular is one that covers a vast amount of research. We have been
Výrost, Tomáš   +2 more
core   +1 more source

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