Results 91 to 100 of about 8,808,149 (269)

Møte i arbeidsgruppen for Oria 28-11-2019

open access: yes, 2019
Referat fra møte i arbeidsgruppen for Oria 28/11 2019.Referat fra møte i arbeidsgruppen for Oria 28/11 ...
Unit
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

PB1986: ADDITION OF CARFILZOMIB AS A THIRD AGENT IN LENALIDOMIDE-REFRACTORY MULTIPLE MYELOMA: SWITCHING FROM DOUBLET TO TRIPLET

open access: yesHemaSphere, 2022
C. Cerchione   +8 more
doaj   +1 more source

Konsortiemøtet i pensumlistekonsortiet 2021

open access: yes, 2021
Referat og sakspapirer fra konsortiemøtet i pensumlistekonsortiet 2021.Referat og sakspapirer fra konsortiemøtet i pensumlistekonsortiet ...
Unit
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Referat styremøte pensumlistekonsortiet 31/03 2020

open access: yes, 2020
Referat fra styremøte i pensumlistekonsortiet 31/3 2020.Referat fra styremøte i pensumlistekonsortiet 31/3 ...
Unit
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

GIRAE: a generalised approach for linking the total impact of invasion to species' range, abundance and per-unit effects. [PDF]

open access: yesBiol Invasions, 2022
Latombe G   +6 more
europepmc   +1 more source

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