Results 81 to 90 of about 1,939,227 (247)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Unit-pricing: Minimising Christchurch Domestic Waste

open access: yes
One economic tool that can aid in the achievement of waste minimisation targets is unit-pricing. Unit-pricing in the waste management sector refers to a pricing system that charges households for their collection and disposal service relative to the ...
Tait, Peter R.
core  

Bidding Behavior in Multi-Unit Auctions - An Experimental Investigation [PDF]

open access: yes
We present laboratory experiments of five different multi-unit auction mechanisms. Two units of a homogeneous object were auctioned off among two bidders with flat demand for two units.
Veronika Grimm, Dirk Engelmann
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Unit Root Properties of Crude Oil Spot and Futures Prices [PDF]

open access: yes
In this paper we examine whether WTI and Brent crude oil spot and futures prices (at one, three and six months to maturity) contain a unit root with one and two structural breaks, employing weekly data over the period 1991-2004. To realize this objective
Russell Smyth, Svetlana Maslyuk
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Unit-root and stationarity testing with empirical application on industrial production of CEE-4 countries

open access: yes
The purpose of this paper is to explain both the need and the procedures of unit-root testing to a wider audience. The topic of stationarity testing in general and unit root testing in particular is one that covers a vast amount of research. We have been
Výrost, Tomáš   +2 more
core  

Are 19 Developed Countries' Real Per Capita GDP levels Non-stationary? A Revisit [PDF]

open access: yes
By using an extended dataset for 19 developed countries, this study employs a recent unit root test to re-examine the issue of the non-stationarity of real per capita GDP.
Shyh-Wei Chen
core  

Using catch-per-unit-effort data to solve spatial problems in Orange Roughy abundance estimates

open access: yes, 2015
This thesis describes a thorough analysis of the Andes Complex orange roughy fishery, which started in 1991 and continues to date. The Andes Complex orange roughy fishery displays a rapid initial decline in catch rate, followed by a prolonged period of ...
Schofield, Max (11705258)   +1 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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