Results 61 to 70 of about 1,939,227 (247)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Raw materials per Stratigraphic Unit (N = total number per SU).

open access: yes, 2018
Raw materials per Stratigraphic Unit (N = total number per SU).
Aurore Val (5663875)   +8 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Regional convergence across European Union [PDF]

open access: yes
This paper analyzes the per-capita incomes convergence process across 140 NUTS2 European regions during the period 1980-1999. Two methods of analysis have been used.
Cristina Brasili, Luciano Gutierrez
core  

Use of Phenomics for Differentiation of Mungbean (Vigna radiata L. Wilczek) Genotypes Varying in Growth Rates Per Unit of Water. [PDF]

open access: yesFront Plant Sci, 2021
Rane J   +8 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Non-Linear Unit Root Properties of Crude Oil Production [PDF]

open access: yes
While there is good reason to expect crude oil production to be non-linear, previous studies that have examined the stochastic properties of crude oil production have assumed that crude oil production follows a linear process.
Russell Smyth, Svetlana Maslyuk
core  

Quantum channel capacities per unit cost

open access: yes, 2019
Communication over a noisy channel is often conducted in a setting in which different input symbols to the channel incur a certain cost. For example, for bosonic quantum channels, the cost associated with an input state is the number of photons, which is
Wilde, Mark M.   +2 more
core   +1 more source

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