Results 101 to 110 of about 136,147 (290)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Effects of Music on Performance and Perceived Exertion [PDF]
Elton Spahiu +2 more
openalex +1 more source
Effect of suspension systems on the physiological and psychological responses to sub-maximal biking on simulated smooth and bumpy tracks [PDF]
The aim of this study was to compare the physiological and psychological responses of cyclists riding on a hard tail bicycle and on a full suspension bicycle. Twenty males participated in two series of tests. A test rig held the front axle of the bicycle
Arthur Whittaker +11 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
PurposeThis study investigated duration-dependent physiological, perceptual, and technical changes during a 2-hour low-intensity training (LIT) session in female cross-country (XC) skiers.MethodsTwelve national-level female XC skiers (age:21.4 ± 2.7 ...
Per-Øyvind Torvik +3 more
doaj +1 more source
Objective: The purpose of this study was to assess whether a lesson of physical activity based on a traditional Tunisian game could be a useful tool for soliciting the cardiovascular system in children.
Johnny Padulo +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Study aim: Recent evidence has revealed a reduction in the strength of correlation between ratings of perceived exertion and a heart rate (HR) derived training load in elite field hockey players during competition.
Perrotta Andrew Scott +1 more
doaj +1 more source

