Results 101 to 110 of about 124,195 (340)
Combining internal- and external-training-load measures in professional rugby league [PDF]
, 2014 Purpose: This study investigated the effect of training mode on the relationships between measures of training load in professional rugby league players.
Abt, Grant +4 more
core +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
The Effect of Secret Clock Manipulation on 10 km Cycle Time Trial Performance. [PDF]
, 2010 The anticipatory RPE feedback model (Tucker 2009) proposes that during self paced exercise tasks, muscular work is continually regulated through comparison of a subconscious ‘template’ Rating of Perceived Exertion (RPE) that serves to protect against the
Renfree, Andrew, Thomas, Gavin
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Fashion and Textiles, 2018 To determine the effects of thermal insulation pads on clothing surface temperature, physical effort and perceived exertion during endurance exercise in cool environments two different pants (PCOOL, PINSUL) were designed: PCOOL (Insulation: 0.055 clo ...
Sebastian Wenger +5 more
doaj +1 more source
Evaluation of the numeric rating scale for perception of effort during isometric elbow flexion exercise [PDF]
, 2011 This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/s00421-011-2074-1.The aim of the study was to examine the reliability and validity of the numerical rating scale (0-10 NRS) for rating ...
Lampropoulou, S, Nowicky, AV
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Physiological, neuromuscular and perceived exertion responses in badminton games
International Journal of Racket Sports Science, 2019 The purpose of this study was to characterise the physiological, neuromuscular and perceived exertion variables during a badminton match and to assess the influence of these variables on the characteristics of the game. Each variable was measured before,
Michael Phomsoupha +3 more
doaj +1 more source
THE RELATIONSHIP BETWEEN MUSCULOSKELETAL STRENGTH, PHYSIOLOGICAL CHARACTERISTICS, AND KNEE KINESTHESIA FOLLOWING FATIGUING EXERCISE [PDF]
, 2012 Fatiguing exercise may result in impaired functional joint stability and increased risk of unintentional injury. While there are several musculoskeletal and physiological characteristics related to fatigue onset, their relationship with proprioceptive ...
Abt, John P +6 more
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