Results 51 to 60 of about 51,431 (308)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Effects of Supplementation with a Vitamin and Mineral Complex with Guaraná Prior to Fasted Exercise on Affect, Exertion, Cognitive Performance, and Substrate Metabolism: A Randomized Controlled Trial

, 2015
Exercise undertaken in a fasted state can lead to higher post-exercise mental fatigue. The administration of a vitamin and mineral complex with guaraná (MVM + G) has been shown to attenuate mental fatigue and improve performance during cognitively ...
Haskell, Crystal, Fuchs, Caspar J., Stevenson, Emma, Kennedy, David, Maggini, Silvia, David Kennedy, Emma Stevenson, Rachel Veasey, Karl Wishart, Caspar Fuchs, Crystal Haskell-Ramsay, Wishart, Karl, Veasey, Rachel, Silvia Maggini   +13 more
core   +1 more source

Perceived Exertion During Endurance Tasks of Abdominal Muscles vs. Electrophysiological Signs of Fatigue—Are They Interchangeable?

Applied Sciences
Abdominal muscles play a crucial role in spinal stability which may be altered by muscular fatigue. To assess the extent of current fatigue, subjective and objective parameters can be used.
Christoph Anders, Christin Alex
doaj   +1 more source

CARDIOVASCULAR RESPONSE TO VERBAL COMMUNICATION A STUDY IN BUSINESS PROCESS OUTSOURCING EMPLOYEES

International Journal of Physiotherapy, 2015
Background: Cardiovascular changes to daily activity and stressors have been proposed as a mechanism for promoting the progression of atherosclerosis and coronary heart diseases.
Divya .P, Veena K. N
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Central and peripheral manipulations of perceived exertion and endurance performance [PDF]

, 2014
Perception of effort, defined as “the conscious sensation of hard, heavy and strenuous exercise”, is known to regulate endurance performance and human behaviour.
Pageaux, Benjamin
core  

A tele-health primary care rehabilitation program improves self-perceived exertion in COVID-19 survivors experiencing Post-COVID fatigue and dyspnea: A quasi-experimental study

, 2022
BACKGROUND: Current evidence suggests that up to 70% of COVID-19 survivors develop post-COVID symptoms during the following months after infection. Fatigue and dyspnea seem to be the most prevalent post-COVID symptoms.
Juan Antonio Valera-Calero, Calvo Paniagua, José, María José Díaz-Arribas, Del Corral Núñez-Flores, Tamara, Gallardo Vidal, María Isabel, Valera-Calero, Juan Antonio, María Isabel Gallardo-Vidal, López-de-Uralde-Villanueva, Ibai, Plaza Manzano, Gustavo, Fernández de las Peñas, César, José Calvo-Paniagua, Gallardo-Vidal, María Isabel, Isabel Gallardo-Vidal, Maria, Ibai López-de-Uralde-Villanueva, del Corral, Tamara, Fernández-de-las-Peñas, César, Plaza-Manzano, Gustavo, Tamara del Corral, Antonio Valera-Calero, Juan, López De Uralde Villanueva, Ibai Julio, Calvo-Paniagua, José, Gustavo Plaza-Manzano, César Fernández-de-las-Peñas, Díaz-Arribas, María José, Díaz Arribas, María José, Valera Calero, Juan Antonio, Jose Diaz-Arribas, Maria   +26 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Caffeine ingestion, affect and perceived exertion during prolonged cycling

, 2011
Caffeine's metabolic and performance effects have been widely reported. However, caffeine's effects on affective states during prolonged exercise are unknown. Therefore, this was examined in the present study.
Williams, C, Biddle, Stuart J. H., Backhouse, Susan H, Backhouse, SH, Susan H. Backhouse, Bishop, Nicolette C., Stuart J.H. Biddle, Williams, Clyde, Clyde Williams, Backhouse, Susan H., Biddle, Stuart, Nicolette C. Bishop, Bishop, NC   +12 more
core   +1 more source

Revista Brasileira de Cineantropometria e Desempenho Humano, 2014
The mechanisms and concepts of perceived exertion have changed over the years. Thus, the objectives of the present literature review were i) to investigate the literature reviews that have been published since 1982 and to describe the proposed causal ...
Gleber Pereira, Douglas Martins de Souza, Felipe Fossati Reichert, Bruno Paula Caraça Smirmaul   +3 more
doaj