Results 61 to 70 of about 51,431 (308)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial

open access: yesJournal of the International Society of Sports Nutrition, 2023
Background Nutrition plays a key role in training and athletic performance and dietary supplements can make a small, but potentially valuable, contribution to achieving peak athletic performance.
Renee Nicole Harrington
doaj   +1 more source

Relationships between external loads, sRPE-load, and self-reported soreness across a men’s collegiate soccer season

open access: yesBiology of Sport, 2023
The purpose was to examine relationships between external loads (ELs), perceived exertion, and soreness. Collegiate men soccer players (n = 19) were monitored for 72 sessions (training: n = 53; matches: n = 19).
Nicholas Kuhlman   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Examining physical training versus physical and mental training programmes in Swimrun semi-professional athletes: A randomised, controlled, trial [PDF]

open access: yesJournal of Health and Social Sciences, 2016
Objective: The purpose of this study was to identify the effect of two psychological interventions, named ‘Mental imagery’ and ‘Motivational self-talk’ training used in combination, on perceived excertion and flow state in a sample of Swimrun semi ...
Francesco Chirico   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The role of lyrics in music–exercise performance on perceived exertion

open access: yesTürk Spor ve Egzersiz Dergisi, 2015
The research aimed to examine the role of lyrics in music on perceived exertion of male and female students during physical activity (running on treadmill).
Ehsan Zareıan   +2 more
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Effect of varied music applications in cycle ergometry [PDF]

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel UniversityThe aim of this research programme was to investigate the effects of different music applications: The differentiated exposure of music and the ...
Lim Ban Teck, Harry
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy