Results 111 to 120 of about 2,726,873 (304)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Perceived social support, depression, and perceived stress in university students

Archives of Advances in Biosciences, 2013
      Psychological disorders are universally common problems. Social support contributes much to the health of individuals. Focusing upon social support and upon vicissitudes of life can help prevent the depression-induced disorders. The present paper investigated the relationship between perceived social support, depression and perceived stress in ...
Ramezankhani, Ali, Gharlipour, Zabihollah, Babaei Heydarabadi, Akbar, Tavassoli, Elahe, Motalebi, Masoud, Barekati, Hasan, Gilasi, Hamid Reza, Kermani Ranjbar, Tahereh, Moosavi, Seyed Akbar   +8 more
openaire   +1 more source

Perceived stress and its relationship with perceived social support in women undergoing chemotherapy for reproductive system cancers

حیات, 2018
Background & Aim: Women with cancer face many stresses. Social support can facilitate coping skills and improve active coping strategies. The purpose of this study was to assess perceived stress and its relationship with perceived social support in women
Fahimeh Sehhati Shafaei, Mojgan Mirghafourvand, Mina Hoseinzadeh   +2 more
doaj  

Inequality and happiness: When perceived social mobility and economic reality do not match [PDF]

In this paper, we revisit the association between happiness and inequality. We argue that the interaction between the perceived and the actual fairness of the income generation process affects this association.
Bjornskov, Christian, Dreher, Axel, Fischer, Justina AV, Schnellenbach, Jan   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Relationship Between Nomophobia, Perceived Stress, and Perceived Social Support Among Medical Students at Mazandaran University of Medical Sciences in 2023 [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: The use of smartphones has significantly increased among students. Although this technology offers various benefits, its misuse can lead to negative consequences, such as nomophobia.
Saeed Barzegari, Seif Ali Mahdavi, Noushin Mousazadeh, Masoume Alinejad, Seyed Alireza Hasani, Kamaledin Alaedini Shourmasti   +5 more
doaj  

Investigation of the Resilience, Self-Efficacy, and Perceived Social Support of Gifted Students

Ankara Üniversitesi Eğitim Bilimleri Fakültesi Özel Eğitim Dergisi
Introduction: This research aimed to analyze the levels of psychological resilience in terms of different variables, self-efficacy, and perceived social support among gifted students, investigate the relationships between these variables, and examine the
Ayşegül Kılıçaslan Çelikkol, Özge Yıldırım   +1 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Comparing Perceived Social Support and Perceived Stress in Women with and without Polycystic Ovary Syndrome Refereed to Fatemiyeh Hospital in Hamadan City

پژوهان, 2018
Background and Objectives: Polycystic Ovary Syndrome is a common issue that affects womens in pregnant age and international statistics indicate that this syndrome is increasing. The aim of this study was to compare perceived social support and perceived
Fatemeh Shobeiri, Maryam Ataollahi, Safoura Jahanara, Ghodratollah Roshanaei   +3 more
doaj