Results 91 to 100 of about 659,643 (306)

Perceived parenting and social support: can they predict academic achievement in Argentinean college students? [PDF]

open access: yes, 2014
The aim of this study was to test the ability to predict academic achievement through the perception of parenting and social support in a sample of 354 Argentinean college students. Their mean age was 23.50 years (standard deviation =2.62 years) and most
Fernandez Liporace, Maria Mercedes   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Social Support and the Perception of Geographical Slant.

open access: yes, 2011
The visual perception of geographical slant is influenced by physiological resources, such as physical fitness, age, and being physically refreshed. In two studies we tested whether a psychosocial resource, social support, can also affect the visual ...

core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Online social support: an exploratory study of breastfeeding women’s use of internet and mobile applications to obtain peer support [PDF]

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Online social support is reported to be used by a number of people to obtain social interaction and exchange communication as a way to buffer stressful ...
Burman, Ana Beatriz Santana
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Relationship Between Perceived Social Support and Anxiety in Pregnant Women With a History of Abortion [PDF]

open access: yesJournal of Holistic Nursing and Midwifery
Introduction: Abortion is a shocking and traumatic event that can lead to psychological disorders, such as anxiety, in women. Perceived social support of these women can be an appropriate method for helping them deal with challenging life events after ...
Fateme Kadkhodaei   +3 more
doaj  

The neural correlates of perceived social support and its relationship to psychological well-being

open access: yesFrontiers in Behavioral Neuroscience
IntroductionPerceived social support is considered to play a significant role in promoting individuals’ health and well-being, and yet the neural correlates of perceived social support were not fully understood. An exploration of the neural correlates of
Huanhua Lu   +3 more
doaj   +1 more source

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