Results 71 to 80 of about 2,726,873 (304)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Maternal Characteristics and Child Problem Behaviors: A Comparison of Foster and Biological Mothers [PDF]

, 2007
The purpose of this exploratory study was to compare the parenting behavior, stress and support of foster mothers and biological mothers of young children.
Byrnes, Judith B., Fox, Robert A., Lucey, Rose   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Perceived Social Support and Social Appearance Anxiety After Bariatric Surgery [PDF]

Journal of Client-centered Nursing Care
Background: Patients undergoing bariatric surgery may need much more psychological and social support from their family and friends to maintain weight loss, recover, and cope with social appearance anxiety.
Aliye Okgün Alcan, Meryem Yavuz van Giersbergen, Oğuz Doğan   +2 more
doaj  

The Influence of Mindfulness and Perceived Social Support on Burnout in Teachers with Students with Special Needs

Tazkiya Journal of Psychology
This study aims to determine the effect of Mindfulness and Perceived Social Support on all dimensions of Burnout. The sample in this study consisted of 212 teachers with students with special needs. The sampling technique used is non-probability sampling.
Hanifah Rizki Nurrahmawati, Zahrotun Nihayah   +1 more
doaj   +1 more source

The motivational atmosphere in youth sport: coach, parent, and peer influences on motivation in specializing sport participants [PDF]

, 2010
This study qualitatively examined the motivationally relevant behaviors of key social agents in specializing sport participants. Seventy-nine participants (9-18 years old) from 26 sports participated in semi-structured focus-groups investigating how ...
Harwood, Chris, Keegan, Richard, Lavallee, David, Spray, Christopher   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Perceived social support and loneliness

, 2023
So far, public health research paid relatively little attention to the association of factors related to social and community networks with health outcomes. There is a need to gain a better understanding of associations between ‘social factors’ and health and wellbeing in all stages of life.
openaire   +1 more source