Results 81 to 90 of about 2,726,873 (304)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
An Empirical Examination of the Associations Among Crystal Methamphetamine Use History, Posttraumatic Stress Symptom Severity, and Perceived Social Support [PDF]
, 2013 Social support functions as a protective factor against the development of posttraumatic stress disorder (PTSD). Crystal methamphetamine use, however, is associated with a decrease in Social functioning.
Dutton, Courtney Elaine
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Journal of Pediatric Research, 2019 Aim:The aim of this study is to determine the correlation between the perceived social support and burnout levels of the mothers of intellectually disabled (ID) children and the affecting factors.Materials and Methods:This descriptive and cross-sectional
İlknur Kahrıman +2 more
doaj +1 more source
Fatalism, Social Support and Mental Health in Four Former Soviet Cultures [PDF]
, 2002 Research on social support has identified differences in levels of support between cultures, but has provided only a limited explanation of the role of values or beliefs in accounting for such variations. In this paper we examine the relationship between
Allen, P +6 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Depression and Perceived Social Support in the Elderly
Sālmand, 2017 Objectives The purpose of the study was to determine depression and perceived social support and some related factors among the elderly people in urban areas of Tehran in the area of Shahid Beheshti University of Medical Sciences.
Maryam Bakhtiyari +4 more
doaj
From Death Notification Through the Funeral: Bereaved Parents’ Experiences and their Advice to Professionals [PDF]
, 2004 Parents who experience the sudden death of a child will interact with many professionals in the period immediately following the death notification through to the funeral. The way these professionals respond to the parents during this critical period may
Cadell, Susan +2 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Perceived Social Support of Older Adults in Spain
Applied Research in Quality of Life, 2012 Based on theory, perceived social support is a relevant multidimensional factor for the wellbeing and quality of life of older adults. However, not all measuring instruments are able to identify this multidimensionality in every population. In this sense, the objectives of this paper are: 1) to identify the dimensions underlying the social support ...
Ahmed Mohamed, Karim +4 more
openaire +2 more sources