Results 111 to 120 of about 804,363 (217)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Adjustment of the Auxiliary Variable(s) for Estimation of a Finite Population Mean [PDF]

open access: yes
In this paper we have worked to weight and transform various estimators by Prasad (1986) and Lui (1991). We have introduced some ratio and ratio type estimators under weighting, transformation and model based approach, environment.
Ayesha, Nazuk   +2 more
core   +1 more source

State-based Climate Legislation: A Policy Analysis of Carbon Tax Proposals in Vermont, New York, and Massachusetts [PDF]

open access: yes, 2018
To date, there are a number of states that have proposed a carbon tax with meaningful support behind them. This paper will focus on New York, Massachusetts, and Vermont due to their political backing as well as each state’s participation in the Regional ...
Doane, John
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Endogenous Wage Rigidity [PDF]

open access: yes
We use a random survey of Swedish human resource managers to study the reasons for wage rigidity. Our findings are as follows. First, during the exceptional recession of the 1990s only 1.1 percent of workers received a wage cut.
Agell, Jonas, Bennmarker, Helge
core  

Inflation and unemployment revisited: grease vs. sand [PDF]

open access: yes, 1998
As inflation rates in the United States decline, analysts are asking if there are economic reasons to hold the rates at levels above zero. Previous studies of whether inflation "greases the wheels" of the labor market ignore inflation's potential for ...
Groshen, Erica L., Schweitzer, Mark E.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Community Perceptions of Unmeasured Quality Improvement in Goods and Services [PDF]

open access: yes
Because of the costs involved in such exercises, current productivity measures do not necessarily fully take into account changes in the quality of goods and services over time.
Ian Black
core  

Think Outside the Color Box: Probabilistic Target Selection and the SDSS-XDQSO Quasar Targeting Catalog

open access: yes, 2011
We present the SDSS-XDQSO quasar targeting catalog for efficient flux-based quasar target selection down to the faint limit of the Sloan Digital Sky Survey (SDSS) catalog, even at medium redshifts (2.5
Abazajian   +69 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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