Results 31 to 40 of about 159,648 (220)

Efficient Difference and Ratio-Type Imputation Methods under Ranked Set Sampling

Axioms, 2023
It is well known that ranked set sampling (RSS) is more efficient than simple random sampling (SRS). Furthermore, the presence of missing data vitiates the conventional results.
Shashi Bhushan, Anoop Kumar, Tolga Zaman, Aned Al Mutairi   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Impact of Accumulated Dust on Performance of Two Types of Photovoltaic Cells: Evidence from the South of Jordan

International Journal of Renewable Energy Development, 2022
This paper examines the impact of accumulated dust on two types of photovoltaic (PV) cells in the performance of solar panels facility located in the southern part of Jordan between January to August 2020.
Abdullah Marashli, Ghadeer Nyazi Al Shaba'an, Waed Al-Twaissi, Mohammad Shalby, Hani Al-Rawashdeh   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Investment Policies to Extend the Life of Expressways in Japan

Discrete Dynamics in Nature and Society, 2017
This study examines the macroeconomic effects of investment policies aimed at extending the life of expressways in Japan based on a stochastic Ramsey model.
Hideo Noda, Yuichi Osano
doaj   +1 more source

Estimating relative sunshine duration from commonly available meteorological variables for simulating biome distribution in the Carpathian Region

Hungarian Geographical Bulletin, 2022
Bright sunshine duration (BSD) data are required for simulating biomes using process-based vegetation models. However, monthly global paleoclimate datasets that can be used in paleo data–model comparisons do not necessarily contain BSD or radiation data.
Zoltán Szelepcsényi, Hajnalka Breuer, Nándor Fodor   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Effect and Efficiency of Municipal Solid Waste Compost and Vermicompost on Morpho-Physiological Properties and Yield of Canola under Drought Stress Conditions [PDF]

Journal of Agricultural Science and Sustainable Production, 2012
In order to study the effect and efficiency of municipal solid waste compost and vermicompost on morpho-physiological properties and yield of canola under drought stress conditions, an experiment was conducted as factorial arrangement based on randomized
Mahdi Rashtbari, Hossein Ali Alikhani
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source