Results 61 to 70 of about 6,718,749 (239)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An Analysis of Allocative Efficiency of Wheat Growers in Northern Pakistan [PDF]
Restricted translog production model is used to estimate the allocative efficiency of wheat growers in Peshawar Valley. It is found that average allocative efficiency is 72 percent.
Dilawar Khan, Muhammad Bashir
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Relative efficiency of higher education in Croatia and Slovenia: an international comparison [PDF]
The article measures the relative efficiency of government spending on higher education in selected new EU member states (with special focus on Croatia and Slovenia) in comparison to selected OECD countries. The article applies a non-parametric approach,
Alka Obadić, Aleksander Aristovnik
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
CrystalsA novel, highly efficient terahertz fully polarized transmission line is designed by two-dimensional tellurium photonic crystals consisting of square lattice rod arrays with a complete photonic bandgap.
Yong Wang +12 more
doaj +1 more source
Increased Statistical Efficiency in a Lognormal Mean Model
Journal of Probability and Statistics, 2014 Within the context of clinical and other scientific research, a substantial need exists for an accurate determination of the point estimate in a lognormal mean model, given that highly skewed data are often present.
Grant H. Skrepnek, Ashok Sahai
doaj +1 more source
AN EXAMINATION OF ECONOMIC EFFICIENCY OF RUSSIAN CROP OUTPUT IN THE REFORM PERIOD [PDF]
This paper examines economic efficiency of Russian corporate farms for 1995-98. Economic efficiency declined over the period, due to declines in both technical and allocative inefficiency.
Trueblood, Michael A., Osborne, Stefan
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source