Results 61 to 70 of about 159,648 (220)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Evaluation of Technical Efficiency in Indian Sugar Industry: An Application of Full Cumulative Data Envelopment Analysis [PDF]

open access: yesEurasian Journal of Business and Economics, 2012
This study focuses on the inter-temporal and inter-state variations in technical and scale efficiency levels of Indian sugar industry. In the first stage, full cumulative data envelopment analysis (FCDEA) is used to derive efficiency scores for 12 ...
Sunil KUMAR, Nitin ARORA
doaj  

A new novel index for evaluating model performance

open access: yesJournal of Natural Resources and Development, 2014
A vast array of scientific literature is concerned with simulation models. The aim of models is to predict the unknown situation as close to as real one. To do this, models are validated and examined for their performance under known condition.
M. H. Ali, I. Abustan
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Study on a Mid-Temperature Trough Solar Collector with Multisurface Concentration

open access: yesInternational Journal of Photoenergy, 2015
A new trough solar concentrator which is composed of multiple reflection surfaces is developed in this paper. The concentrator was analyzed firstly by using optical software.
Zhengliang Li   +4 more
doaj   +1 more source

Experimental Investigation on Brake Thermal Efficiency and Emission Characteristics of Plastic Oil-Mahua Biodiesel Blends in CRDI Diesel Engine [PDF]

open access: yesEPJ Web of Conferences
The adoption of sustainable fuels has gained momentum due to increased environmental awareness issues and increased energy needs in the world. This study is concerning the use of biodiesel produced out of plastic oil and Mahua oil methyl ester (PMME) in ...
Jayapalan Senthil   +4 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Application of Bounded Data Envelopment Analysis to Evaluate Efficiency of Broiler Firms (Case study: South Khorasan Province)

open access: yesمجله اقتصاد و توسعه کشاورزی, 2014
Analyzing efficiency in each economic sector to adopt policies for optimal use of production factors and avoid wasting resources is important. In this study, in order to have a more comprehensive evaluation of the performance of each unit, efficiency of ...
jafar esfahani
doaj  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

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