Results 61 to 70 of about 44,104 (282)

Targeted Lipidomics Reveal the Effect of Perchlorate on Lipid Profiles in Liver of High-Fat Diet Mice

Frontiers in Nutrition, 2022
Perchlorate, commonly available in drinking water and food, acts on the iodine uptake by the thyroid affecting lipid metabolism. High-fat diets leading to various health problems continually raise public concern.
Qiao Wang, Wanying Song, Yimei Tian, Peihao Hu, Xin Liu, Lin Xu, Zhiyong Gong   +6 more
doaj   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Exposure to perchlorate via drinking water from eight major water basins in China and its health risks across different age groups

Scientific Reports
Perchlorate is widely used in various industrial fields and has been widely detected in aquatic environments because of its high solubility and stability.
Jia Lyu, Yongyan Chen, Lan Zhang, Xu Yan, Muyesaier Tudi   +4 more
doaj   +1 more source

Molecular adaptations specific to extreme halophilic archaea could promote high perchlorate tolerance

Applied and Environmental Microbiology
Perchlorate is a strong chaotropic agent that causes macromolecule denaturation, DNA damage, and oxidative stress. However, perchlorate deliquescence is thought to promote the formation of liquid salt brines, even at hyper-arid and cold environments ...
Jorge Díaz-Rullo, José Eduardo González-Pastor   +1 more
doaj   +1 more source

Risk assessment of dietary exposure to perchlorate and chlorate in infant formula milk powder in Inner Mongolia

Zhongguo shipin weisheng zazhi, 2023
ObjectiveTo understand the pollution level of perchlorate and chlorate in infant formula milk powder in Inner Mongolia evaluate the dietary intake risk of perchlorate and chlorate in infants， and provide a scientific basis for guiding the healthy diet of
LI Suying, HOU Kun, ZHANG Qing, ZHENG Litao, LI Jianing, PU Yunxia, MAO Weifeng   +6 more
doaj   +1 more source

2,6-Diethylanilinium perchlorate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
The asymmetric unit of the title mol-ecular salt, C(10)H(16)N(+)·ClO(4) (-), contains two cations and two anions. The atoms of one of the ethyl side chains of one of the cations are disordered over two sets of sites in a 0.531 (13):0.469 (13) ratio. In the crystal, the components are linked by N-H⋯O and bifurcated N-H⋯(O,O) hydrogen bonds and weaker C ...
Salem S. Al-Deyab, Mohamed Rzaigui, Wajda Smirani Sta   +2 more
openaire   +3 more sources

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

2-Chloroanilinium perchlorate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the crystal of the title compound, C(6)H(7)ClN(+)·ClO(4) (-), a layer-like structure parallel to the bc plane is formed through N-H⋯O hydrogen bonds between the cations and anions. These layers are connected by weak C-H⋯O inter-actions, forming a three-dimensional network.
Benhua Zhou, Jin Cai
openaire   +3 more sources

A Strong Lewis Acidic Diethylsilylium Catalyst for Direct Sulfonamidation of Challenging Ketones

Advanced Science, EarlyView.
Low‐substitution‐order silylium ions (R2HSi+) exhibit exceptional Lewis acidic activity. We report diethylsilylium‐catalyzed reductive sulfonamidation of functionalized ketones to access β‐amino esters. The in situ generated ion pair shows enhanced reactivity, with diethylsilane serving as both reductant and precatalyst. The developed protocol proceeds
Woo Hee Kim, Muhammad Israr, You Kyoung Chung, Shinwon Ham, Joonsuk Huh, Han Yong Bae   +5 more
wiley   +1 more source

Copper(II/III) Redox Couple Enables C─H Methylation via a Radical Mechanism Analogous to SAM Enzymes

Angewandte Chemie, EarlyView.
Biological C–H methylation proceeds through radical pathways mediated by one‐electron redox cofactors, yet no synthetic model has reproduced this reactivity. Here, we report the first isolable Cu(II/III)–methyl complexes that mediate C–H methylation through hydrogen atom transfer and methyl radical rebound.
Emily N. Doss, Curtis E. Moore, Shiyu Zhang   +2 more
wiley   +2 more sources