Results 31 to 40 of about 120,930 (291)

Hamilton and Li–Yau type gradient estimates for a weighted nonlinear parabolic equation under a super Perelman–Ricci flow

open access: yesPartial Differential Equations and Applications
In this paper we derive elliptic and parabolic type gradient estimates for positive smooth solutions to a class of nonlinear parabolic equations on smooth metric measure spaces where the metric and potential are time dependent and evolve under a super ...
Ali Taheri, Vahideh Vahidifar
semanticscholar   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

open access: yesHepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat   +22 more
wiley   +1 more source

Liberdade de Escolha no Serviço Nacional de Saúde - o Caso do VIH

open access: yesActa Médica Portuguesa, 2015
Palavras-Chave: Direitos do Doente; Infecções por VIH/tratamento; Portugal; Serviço Nacional de Saúde; Tomada de Decisão.
Julian Perelman
doaj   +1 more source

Pandemia Sindémica em Portugal: Desigualdade Social nos Fatores de Risco Associados à Mortalidade por COVID-19

open access: yesActa Médica Portuguesa, 2022
Introdução: A evidência internacional tem demonstrado desigualdades sociais no risco de morte por SARS-CoV-2 (COVID-19). Em Portugal, a impossibilidade de identificar a condição socioeconómica dos indivíduos falecidos impede esta medição.
Julian Perelman
doaj   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Harnack Estimates for Conjugate Heat Kernel on Evolving Manifolds

open access: yes, 2014
In this article we derive Harnack estimates for conjugate heat kernel in an abstract geometric flow. Our calculation involves a correction term D. When D is nonnegative, we are able to obtain a Harnack inequality.
Cao, Xiaodong, Guo, Hongxin, Tran, Hung
core   +1 more source

Long-time behavior of 3 dimensional Ricci flow -- A: Generalizations of Perelman's long-time estimates [PDF]

open access: yes, 2014
This is the first of a series of papers on the long-time behavior of 3 dimensional Ricci flows with surgery. In this paper we first fix a notion of Ricci flows with surgery, which will be used in this and the following three papers.
R. Bamler
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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