Results 61 to 70 of about 120,930 (291)

La antinomia del Sr. Gödel

open access: yesEpistemología e Historia de la Ciencia, 2019
Traducción de "L'antinomie de M.
Carlos Alejandro Oller, Chaïm Perelman
doaj   +2 more sources

Neuroplasticity of the Lateral Geniculate Nucleus in Response to Retinal Gene Therapy in a Group of Patients with RPE65 Mutations

open access: yesEye and Brain, 2022
Manzar Ashtari,1– 3 Mikhail Lipin,1,2 Michelle Duong,4 Gui-Shuang Ying,5 Yinxi Yu,5 Albert Maguire,1,2 Jean Bennett1,2 1Department of Ophthalmology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA; 2Department of ...
Ashtari M   +6 more
doaj  

Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics

open access: yesAdvanced Science, EarlyView.
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran   +5 more
wiley   +1 more source

The Anarchy of Globalization: Local and Global, Intended and Unintended Consequences

open access: yesWorld Review of Political Economy, 2015
Globalization is full of contradictions, creating homogeneity alongside differentiation. Classes become more differentiated while products become more homogeneous. Globalization has stimulated growth in China, while it has contributed
Michael Perelman
doaj   +1 more source

2026 Update on the Management of Diffuse Large B‐Cell Lymphoma

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common type of NHL in the Western Hemisphere. It comprises a heterogenous group of lymphomas, with different biology and clinical prognoses. R‐CHP remains the backbone of therapy, and frontline therapeutic options in fit patients are pola‐R‐CHP and R‐CHOP, whereas elderly or frail/unfit ...
Elise A. Chong   +2 more
wiley   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson   +8 more
wiley   +1 more source

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell   +3 more
wiley   +1 more source

Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville   +6 more
wiley   +1 more source

O Conceito de Justiça em Perelman e Rawls

open access: yesRevista de Ciências Jurídicas e Sociais da UNIPAR, 2008
Pesquisa bibliográfica que examina o conceito de justiça de Perelman e de Rawls. Inicia tratando do conceito de justiça de Aristóteles, na Ética a Nicômaco, por ser referência conceitual obrigatória em Filosofia do Direito.
Alvino Moser
doaj  

Yakov Isidorovich Perelman: um pioneiro da divulgação científica esquecido (Parte I: vida e obra) [PDF]

open access: yesRevista Brasileira de Ensino de Física
O presente artigo inaugura uma série de três publicações que investigam a vida e a obra do divulgador científico Yakov Perelman (1882–1942). Perelman é conhecido no Brasil principalmente pelas obras Aprenda Física Brincando e Aprenda Álgebra Brincando ...
Thárcio Adelino Cerqueira   +1 more
doaj   +1 more source

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