Results 41 to 50 of about 2,041,584 (301)
Frontiers in Genetics, 2015 Next generation sequencing (NGS) technologies, primarily based on massively parallel sequencing (MPS), have touched and radically changed almost all aspects of research worldwide.
Brock A Peters +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Perfectionism and emotional reactions to perfect and flawed achievements: Satisfaction and pride only when perfect [PDF]
, 2010 Perfectionists have excessively high standards and thus are prone to experience dissatisfaction and embarrassment. But what if they achieve perfection? The present study investigated in a sample of 194 university students how self-oriented and socially ...
Stoeber, Joachim, Yang, Hongfei
core +1 more source
Almost perfect sequences with $ \theta = 2 $
Archiv der Mathematik, 1998 An almost perfect sequence is a periodic \(\pm 1\)-sequence where all the off-peak autocorrelation coefficients are as small as theoretically possible, with exactly one exception, say \(C(g)\). It is easy to see that the period \(v\) of the sequence has to be even, say \(v= 2m\), and that \(g= m\). By a result of \textit{A. Pott} and \textit{S.
Leung, Ka Hin +3 more
openaire +5 more sources
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
A NOTE ON REPUNIT NUMBER SEQUENCE
IntermathsIn this paper, we investigate the classical identities of the repunit sequence with integer indices in light of the properties of Horadan-type sequences. We highlight particularly the Tagiuri-Vajda Identity and Gelin-Cesàro Identity.
Douglas Catulio Santos +1 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
A Class of Explicit Perfect Multi-sequences [PDF]
, 1999 In [7], perfect multi-sequences are introduced and a construction based on function fields over finite fields is given. In this paper, we explore the construction in [7] by considering rational function fields. Consequently a class of perfect multi-sequences are obtained.
Chaoping Xing +2 more
openaire +2 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source