Results 31 to 40 of about 114,098 (248)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Motivation's Pick-Me-Upper: Enhancing Performance Through Motivation-Enhancing Drugs [PDF]
, 2015 Torben Kjærsgaard’s argues that the term “cognitive enhancement substances” is an inappropriate term considering that stimulants do not enhance cognition, but rather only enhance motivation.
Ray, Keisha Shantel
core
, 2013 The Gateway Hypothesis was examined with respect to appearance- and performance-enhancing substance use. Various sociocultural influences on substance use were also included in the analysis to determine whether prior substance use predicts current use ...
Crowther, J. H. +2 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2013 Sattler S, Forlini C, Racine É, Sauer C. Impact of Contextual Factors and Substance Characteristics on Perspectives toward Cognitive Enhancement. PLoS ONE. 2013;8(8): e71452.Enhancing cognitive performance with substances–especially prescription drugs–is
Racine, Éric +9 more
core +1 more source
Prevalence and social-cognitive determinants of the use of performance enhancing substances by Portuguese gymgoers [PDF]
, 2020 Background: The use of performance-enhancing substances (PES) occurs among gym goers, which is seen as a public health concern. The aim of this study is to investigate the extent of PES use and the social-cognitive determinants whichinfluence the ...
Tavares, A. S. +6 more
core +2 more sources
Effect of cytostatic drugs on the sludge and on the mixed liquor characteristics of a cross-flow membrane bioreactor: Consequence on the process [PDF]
, 2010 The influence of cyclophosphamide and its principal metabolites (CPs) on the physicochemical properties of the mixed liquor of a cross-flow membrane bioreactor and the consequences for membrane fouling were investigated.
Delgado, Luis Fernando +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Are doping substances imported into Switzerland mainly to increase athletic performance
, 2016 Background: Doping substances are those thought to increase athletic performance, enhance image, or overcome the effects of ageing. This study aims to evaluate the profiles of people and the reasons for importing substances appearing on the World Anti ...
Lentillon-Kaestner, Vanessa +2 more
core +1 more source