Results 51 to 60 of about 114,098 (248)

Appearance/Image- and Performance-Enhancing Drug Users: A Forensic Approach

open access: yes, 2018
Image- and performance-enhancing drugs include a wide range of substances used to promote physical changes to enhance appearance. Anabolic androgen steroids are the most widely used image- and performance-enhancing drugs along with a wide variety of ...
Lusetti M.   +19 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Ignorance, Harm, and the Regulation of Performance-Enhancing Substances

open access: yes, 2014
There is a disconnect between how legal and sporting authorities, on the one hand, and many elite athletes, on the other, view the use of performance-enhancing substances.
Milot, Lisa
core  

The Formation and Development of Illicit Performance and Image Enhancing Drug Markets: Exploring Supply and Demand, and Control Policies in Belgium and the Netherlands [PDF]

open access: yes, 2015
This research explores the understudied phenomenon of performance and image enhancing drug (PIED) markets by examining the structure and formation of the market for PIEDs in the Netherlands and Belgium.
van de Ven, K., van de Ven, Katinka
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Protective factors of performance-enhancing substances use in a sample of Portuguese gym-goers [PDF]

open access: yes
This project was supported by national funds through FCT - Fundação para a Ciência e Tecnologia: FCT/MCTES (UIDB/05608/2020 and UIDP/05608/2020).Background: Nowadays, the increased Performance Enhancing-Substance (PES) use in fitness centers is seen as a
Tavares, Ana Sofia   +4 more
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Performance-enhancing substances in sport: An ethical study

open access: yes, 1990
Questions concerning whether current policies restricting the use of performance enhancing substances in sport are morally or ethically justified have not received the attention they deserve from philosophers of sport.
Gardner, Roger William
core  

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