Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Self-Evaluation in Childhood Social Anxiety Disorder: Effects of Repeated Exposure with Support Strategies. [PDF]
Res Child Adolesc PsychopatholVietmeier N +2 more
europepmc +1 more source
Perceived Impact of Performance Appraisal on Employee’s performance
Diksha Yadav
openalex +2 more sources
Systematic Review of Emergency Severity Index (ESI) triage tool's utility in predicting mortality and critical care unit admission in Emergency Departments. [PDF]
Afr J Emerg MedAbdelrazek K +4 more
europepmc +1 more source
Clinical governance and staffing for healthcare quality: perceptions of nurses, doctors, and senior managers at two tertiary hospitals in Jamaica. [PDF]
BMC Health Serv ResThompson C +6 more
europepmc +1 more source
Computer vision applications in vascular surgery: a systematic review and critical appraisal. [PDF]
NPJ Digit MedLiyanage A +4 more
europepmc +1 more source
Constructive Appraisal of "Real-World Study Assessing Sensitivity and Clinical Utility of a Host-Protein Test in Adult Emergency Department Patients With Blood Culture Ordered". [PDF]
J Am Coll Emerg Physicians OpenAphale P, Shekhar H, Dokania S.
europepmc +1 more source