Results 121 to 130 of about 9,431,353 (310)
, 2009 Acknowledgements -- Introduction -- Human enhancement ethics: the state of the debate / Nick Bostrom and Julian Savulescu -- Pt. I. Human enhancement in general -- 1. Can anyone really be talking about ethically modifying human nature?
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Journal of the International Society of Sports NutritionBackground The menopausal transition is characterized by hormonal shifts, particularly a decline in estrogen, which is associated with increased fat mass and reduced lean body mass.
Valeria V. Silva Ramirez +11 more
doaj +1 more source
Frontiers in Physiology, 2019 The role of physical activity in determining the metabolic health of adolescents is poorly understood, particularly concerning the effect on low-grade chronic inflammation (chronic elevation of pro-inflammatory cytokines IL-1β, IL-6, TNF-α and acute ...
Karah J. Dring +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Watershed restoration inventory
, 1998 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.1998-Mode of access: Internet from the Oregon Government ...
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On the sensitivity of the capacity enhancement of a TDMA system with adaptive multibeam antennas [PDF]
, 1997 The paper presents results for the likely capacity improvement when an adaptive multibeam antenna is used in conjunction with air interface parameters akin to the DCS1800 system.
Swales, SC, Tsoulos, GV, Beach, MA
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
SensorsThis study presents an integrated framework for enhancing the safety and operational efficiency of robotic arms in laparoscopic surgery by addressing minimum distance estimation between multi-arm manipulators and the associated collision-aware warning ...
Sarvin Ghiasi +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source