Results 111 to 120 of about 540,835 (313)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Immediate effects of ultrasound therapy on pain and plantar pressure in individuals with subacute ankle sprains: a randomized controlled trial

Physiotherapy Quarterly
Introduction Despite the fact that ultrasound (US) therapy is not advised for acute ankle sprains, its therapeutic effects may be beneficial for other stages of ankle sprains, such as a subacute ankle sprain.
Thongchai Suksri, Chitanongk Gaogasigam, Sujitra Boonyong   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A numerical investigation of heat transfer in phase change materials (PCMs) embedded in porous metals [PDF]

, 2011
The effects of metal foams on heat transfer enhancement in Phase Change Materials (PCMs) are investigated. The numerical investigation is based on the two-equation non-equilibrium heat transfer model, in which the coupled heat conduction and natural ...
Zhao, Changying, Tian, Yuan, Tian, Y. (Yuan), Y. Tian, C.Y. Zhao, Zhao, C.Y.   +5 more
core   +1 more source

Chronological age and biological maturity are separately positively associated with inhibitory control and working memory in boys and girls

Frontiers in Cognition
Executive function is typically considered from a chronological age perspective, despite the influence of biological maturity on executive function development.
Luke M. Gilbert, Ryan A. Williams, John G. Morris, Anna Dunn, Ruth Boat, Karah J. Dring, Mary E. Nevill, Simon B. Cooper   +7 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Nintendo Ring Fit Adventure improves balance ability in sedentary young adults

Physiotherapy Quarterly
Introduction Exercising with a game console is a novel type of exercise. One game that is currently popular is Nintendo Ring Fit Adventure, but its impact on balancing ability in young adults who are sedentary has yet to be investigated. This study aimed
Akkradate Siriphorn, Chayanuch Jirawadeenichada, Jirawat Kotcharak, Kairawee Kiatkaiwansiri, Siriporn Vongsaiyat Siriphorn   +4 more
doaj   +1 more source

Multi-Stage Fitness Test Performance, V˙O2 Peak and Adiposity: Effect on Risk Factors for Cardio-Metabolic Disease in Adolescents

Frontiers in Physiology, 2019
The role of physical activity in determining the metabolic health of adolescents is poorly understood, particularly concerning the effect on low-grade chronic inflammation (chronic elevation of pro-inflammatory cytokines IL-1β, IL-6, TNF-α and acute ...
Karah J. Dring, Simon B. Cooper, John G. Morris, Caroline Sunderland, Gemma A. Foulds, Alan Graham Pockley, Mary E. Nevill   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Survey study of changes in total caloric and protein intake across the menopause transition: a preliminary analysis

Journal of the International Society of Sports Nutrition
Background The menopausal transition is characterized by hormonal shifts, particularly a decline in estrogen, which is associated with increased fat mass and reduced lean body mass.
Valeria V. Silva Ramirez, Anna Oelmann, John Holtje, Landon Shannahan, Gretchen Shelton, Nam Nguyen, Stacy T. Sims, Jacey A. Greece, Laura Pyott, Gabrielle Lyon, Michael J. Ormsbee, Bill I. Campbell   +11 more
doaj   +1 more source