Results 91 to 100 of about 1,685,327 (341)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background Hormone Replacement Therapy (HRT) is considered the gold standard for management of vasomotor symptoms. It can also help improve bone health, potentially reducing the risk of osteoporosis and fractures.
John Holtje +11 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Performance evaluation and enhancement of Dendro [PDF]
DENDRO is a collection of tools for solving Finite Element problems in parallel. This package is written in C++ using the standard template library (STL) and uses the Message Passing (MPI). Dendro uses an octree data-structure to solve image-registration
Mukherjee, Jayanta
core
Bioethics of military performance enhancement [PDF]
Biological interventions to improve performance, such as amphetamines, have a long history of military use, and in the future may include more advanced biotechnologies. This article discusses the ethics of using biomedical enhancements in the military.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Enhancement of thrust reverser cascade performance using aerodynamic and structural integration [PDF]
This paper focuses on the design of a cascade within a cold stream thrust reverser during the early, conceptual stage of the product development process.
Armstrong, Cecil +7 more
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Introduction Despite the fact that ultrasound (US) therapy is not advised for acute ankle sprains, its therapeutic effects may be beneficial for other stages of ankle sprains, such as a subacute ankle sprain.
Thongchai Suksri +2 more
doaj +1 more source

