Results 81 to 90 of about 540,835 (313)

Sprint-based exercise and cognitive function in adolescents

Preventive Medicine Reports, 2016
Moderate intensity exercise has been shown to enhance cognition in an adolescent population, yet the effect of high-intensity sprint-based exercise remains unknown and was therefore examined in the present study.
Simon B. Cooper, Stephan Bandelow, Maria L. Nute, Karah J. Dring, Rebecca L. Stannard, John G. Morris, Mary E. Nevill   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Self-enhancement and self-protection: what they are and what they do [PDF]

, 2009
We define self-enhancement and self-protection as interests that individuals have in advancing one or more self-domains or defending against negative self-views. We review ways in which people pursue self-enhancement and self-protection, discuss the role
Sedikides, Constantine, Constantine Sedikides, Alicke, Mark D., Mark D. Alicke   +3 more
core   +1 more source

Effects of heat stress and dehydration on cognitive function in elite female field hockey players

BMC Sports Science, Medicine and Rehabilitation, 2018
Background It has previously been suggested that heat exposure and hypohydration have negative effects on cognitive performance, which may impact upon sporting performance.
Hannah MacLeod, Simon Cooper, Stephan Bandelow, Rachel Malcolm, Caroline Sunderland   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Investigating weight loss resistance across the menopausal transition: a preliminary quantitative survey of resistance-trained women

Journal of the International Society of Sports Nutrition
Background Many women enter midlife unaware of the physiological and hormonal changes associated with the menopause transition. This period is commonly characterized by increased fat mass and decreased lean body mass.
Anna Oelmann, John Holtje, Valeria V. Silva Ramirez, Nam Nguyen, Landon Shannahan, Gretchen Shelton, Jacey Greece, Laura Pyott, Vince Pitstick, Cassidy Bale, Bill I. Campbell   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Examining the associations of self-control with physical fitness, cardiometabolic health, and well-being in young people aged 9–13 years

Frontiers in Cognition
BackgroundPrevious research has demonstrated that high self-control is associated with cardiorespiratory fitness and physical activity in young people.
Anna Dunn, Ryan A. Williams, Karah J. Dring, Simon B. Cooper, Ruth Boat   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source