Results 261 to 270 of about 6,335,595 (355)

Design optimization and performance evaluation of semi-prefabricated UHPC-RC metro station structures. [PDF]

Sci Rep
Lei G, Hua F, Yang Z, Jiang F, Zhu J.
europepmc   +1 more source

Evaluation of the Potential Performance of Hospital Buildings in Windstorms

, 1978
Patrick Alan Lea
openalex   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A One Health performance evaluation system for urban parasitic disease prevention and control: The Shanghai, China pilot scheme. [PDF]

One Health
Zhang X, Dong X, Liu X, Wei Z, Liu Y, Chen M, Hao Y, Sun J, Zhou X, Yu Q, Li S.   +10 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

One-Step Synthesis and Performance Evaluation of a Sucrose-Glyoxylic Acid Wood Adhesive. [PDF]

Materials (Basel)
Liang J, Yang Y, Wu L, Zuo N, Li Q, Meng T, Chen C, Li H, Long C, Song Z, Jian Y, Li, Wu Z.   +12 more
europepmc   +1 more source

Evaluation of Mechanical Performance as Indicated by Lightweight In-Situ Monitoring Sensor Modalities in LPBF

Cody Lough, Jon Zettwoch, Noah Welch, Ben Brown   +3 more
openalex   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Performance Evaluation of a Novel Digital Flow-Imaging IV Infusion Device. [PDF]

IEEE Open J Eng Med Biol
Butterfield RD, Sims NM.
europepmc   +1 more source