Results 171 to 180 of about 5,818,212 (310)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Interdisciplinary Health and Performance Management of the Sliding Athlete: A Clinical Commentary. [PDF]

Int J Sports Phys Ther
Faltus J, Knowlton-Key J, Howard K, Doorley J, Towne B, Kannel C, Finnoff J, Donaldson A.   +7 more
europepmc   +1 more source

Knowledge, Understanding and Satisfaction with the Implementation of the Performance Management System at a District Hospital in the Madibeng Subdistrict, South Africa. [PDF]

Int J Environ Res Public Health, 2022
Thobejane G, van der Heever H, Mokgatle M.   +2 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Intelligently driven performance management: an enabler of real-time research forecasting for innovative commercial agriculture. [PDF]

SN Soc Sci, 2022
Abeysiriwardana PC, Jayasinghe-Mudalige UK, Kodituwakku SR, Madhushani KB.   +3 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Personalized AI for workplace health promotion: performance management and healthcare worker engagement through digital analytics. [PDF]

Front Public Health
Virgillito D, Ledda C.
europepmc   +1 more source

Weightlifting competitions: lessons for performance management [PDF]

Christos Genakos and Mario Pagliero look at professional weightlifters to assess the effects of reward systems based on relative performance.
Christos Genakos, Mario Pagliero
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Soldier performance management: insights from boots on ground research and recommendations for practitioners. [PDF]

BMJ Mil Health
Main LC, Maroni TD, Ojanen T, Drain JR, Nindl B.   +4 more
europepmc   +1 more source