Results 131 to 140 of about 12,134,415 (311)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Distorted performance measurement and relational contracts [PDF]
This paper analyzes the use of alternative performance measures in an agency model in which contracting incorporates both formal and informal agreements.
Budde, Jörg
core
Representing the output of the research project "Performance: Conservation, Materiality, Knowledge," this volume brings together diverse voices, methods, and formats in the discussion and practice of performance conservation.
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Performance measurement : challenges for tomorrow [PDF]
, 2012 This paper demonstrates that the context within which performance measurement is used is changing. The key questions posed are: Is performance measurement ready for the emerging context? What are the gaps in our knowledge?
Dörfler, Viktor +3 more
core +1 more source
A study of desmosome formation in kidney epithelial cells
, 1988 Desmosomes are intercellular junctions mediating cell-cell adhesion. When epithelial cells are cultured in medium of low calcium concentration (< 0.05mM, LCM) desmosomes do not form but do so when the external calcium concentration is raised above 0.1
Measures, Helen Rachel
core +1 more source
On Performance Measures of a Fuzzy Priority Queue in a Transient Regime using the L-R Method
InPrimeIn this paper, we proposed the performance measures of a Markovian queue with non-preemptive priority under transient conditions in a fuzzy environment. We study the transient performance measures of an FM/FM/1 queue with absolute priority.
Daniel Lama Okenge +3 more
doaj +1 more source