Results 131 to 140 of about 12,947,404 (311)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Risk mitigation of performance ratio guarantees in commercial photovoltaic systems [PDF]
: This study demonstrates the importance of managing the risk of performance ratio guarantees, which typically are applicable to most commercial PV projects.
Pretorius, J.C., Basson, H.A.
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Clipping-corrected performance ratio: a new metric for high DC:AC ratio PV systems
The most established key performance indicator for (PV) system performance is the performance ratio (PR) metric, which is the ratio of the actual to the expected specific yield of a PV system.
Blakesley James C. +5 more
doaj +1 more source
Wetland Dwellers: Sound Performance Walk
A Performance Sound walk Shire Brook Valley and Woodhouse Washlands in South Yorkshire with Gary Stewart (Goldsmiths), Sam Vardy (SHU), Phil Warren (SU), Sheffield wildlife trust.
McCloskey, P.
core
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Energy Performance Contracting for Solar PV in the Public Sector: Performance and Carbon Mitigation
Energy Performance Contracting (EPC) is increasingly used as a financial mechanism to accelerate renewable energy investments in public infrastructure; however, its effectiveness depends not only on technical performance but also on institutional ...
Anna Szeląg-Sikora +9 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The DC/AC ratio is a critical design variable in utility-scale photovoltaic (PV) systems because it governs inverter loading, clipping behavior, energy yield, and long-term economic performance.
Orhan Türkoğlu, Muhammet Arucu
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source

