Results 121 to 130 of about 1,885,562 (317)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Reliability Analysis of Residential Photovoltaic Systems Across Five Climatic Zones: Performance, Degradation, and Fault Trends

Energies
This study analyses the long-term reliability of 100 residential PV systems monitored for 7–11 years across 33 countries and five climate zones. System performance was evaluated using the temperature-corrected performance ratio (PRTcorr), following IEC ...
Mahmoud Dhimish, Romênia Vieira, Peter Behrensdorff Poulsen   +2 more
doaj   +1 more source

Temperature impact on dusty and cleaned photovoltaic module exposed in sub-Saharan outdoor conditions

EPJ Photovoltaics, 2018
In this work, impacts of temperature and dust cleaning on photovoltaic module performance operating in sub-Saharan's climate are investigated. Two single junction technologies, monocrystalline and polycrystalline silicon, and one micromorph (amorphous ...
Kata N'detigma, Soro Y. Moussa, Diouf Djicknoum, Darga Arouna, Maiga A. Seidou   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Price Earning Ratio and Market to Book Ratio

This paper studies the effects of P/E ratio and M/B ratio on stock return of listed firms with Karachi Stock Exchange in the Textile sector of Pakistan. A total of 30 major firms out of 162 in the textile sector listed with the Karachi Stock Exchange for
Khan, Muhammad Irfan
core  

Influence of Semi-Arid Environmental Conditions on PR and PLR of a 150 kWp Photovoltaic System

IEEE Access
This article presents an analysis of the operational performance and degradation of a 150 kWp grid-connected photovoltaic (PV) power plant located in the Brazilian semi-arid region.
Jose Ragner Brito De Sousa, Dulciel Marcos Abel Da Silva, Romenia G. Vieira   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

PV System Performance Analysis and Forecasting Using Deep Learning and Statistical Methods

Energies
This study investigates the long-term performance degradation and forecasting of three silicon-based photovoltaic technologies—polycrystalline (pc-Si), monocrystalline (mc-Si), and amorphous silicon (a-Si)—using a seven-year dataset (2015–2021) from a ...
Mustapha Adar, Mohamed-Amine Babay, Mustapha Mabrouki   +2 more
doaj   +1 more source

ANALYSIS OF LIQUIDITY RATIOS AND PROFITABILITY RATIOS TO ASSESS FINANCIAL PERFORMANCE

International Journal of Accounting, Management, Economics and Social Sciences (IJAMESC)
PT. GoTo Gojek Tokopedia Tbk experienced a profit that continued to decline from 2019 to 2022. The purpose of this study is to determine how the profitability ratio is seen from  gross profit margin, net profit margin, return on assets,  and return on equity at PT.
null Novi Tri Asiani, null Ni Putu Widhia Rahayu   +1 more
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source